Superior Laryngeal Nerve Block Response Rates in 54 Neurogenic Cough Patients.
Cough/PVFM/Irritable Larynx
chronic cough
neurolaryngology
quality of life
superior laryngeal nerve
Journal
The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
revised:
06
12
2022
received:
24
08
2022
accepted:
02
01
2023
medline:
20
9
2023
pubmed:
24
1
2023
entrez:
23
1
2023
Statut:
ppublish
Résumé
Neurogenic cough related to hypersensitivity of the internal branch of the superior laryngeal nerve (SLN) is often treated with neuromodulating medications, which can cause considerable side effects. An alternative therapy is steroid and local anesthetic injection of the SLN ("SLN block"), initially proposed to benefit those with lateralizing symptoms (tenderness over the thyrohyoid membrane or unilateral cough source). Our objectives are to determine if SLN block produces subjective symptomatic improvements and if repeat injections further improve symptoms, and evaluate clinical factors potentially predictive of response. Retrospective chart review of 54 patients receiving SLN blocks at a tertiary medical academic center from January 2010 to June 2020. Medical history and anticipated predictors of positive response, including stigmata of laryngeal hypersensitivity, were recorded. Outcomes included symptomatic response, number of injections required, and side effects. Response was defined subjectively by asking patients whether the injection was beneficial and objectively by using CSI scores. Fifty-four patients met the inclusion criteria. Thirty-eight patients (70.4%) endorsed improvement. No variables were identified as positive predictors of response. Thirty-two of the 38 (84.2%) endorsed improvement after one injection. Six of 15 (40%) patients who failed the first injection had positive response to the second. No significant side effects were reported. No localizing symptoms, specific cough features, or aspects of the medical history helped predict response, suggesting that a broader range of patients may be offered the intervention. The majority of patients reported symptomatic improvement and repeat injections may benefit patients with initial nonresponse. 4 Laryngoscope, 133:2647-2653, 2023.
Substances chimiques
Anesthetics, Local
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2647-2653Informations de copyright
© 2023 The Authors. The Laryngoscope published by Wiley Periodicals LLC on behalf of The American Laryngological, Rhinological and Otological Society, Inc.
Références
Roe NA, Lundy FT, Litherland GJ, McGarvey LPA. Therapeutic targets for the treatment of chronic cough. Curr Otorhinolaryngol Rep. 2019;7:116-128. https://doi.org/10.1007/s40136-019-00239-9.
Ford AC, Forman D, Moayyedi P, Morice AH. Cough in the community: a cross sectional survey and the relationship to gastrointestinal symptoms. Thorax. 2006;61(11):975-979. https://doi.org/10.1136/thx.2006.060087.
National Center for Health Statistics. National Ambulatory Medical Care Survey, 2018. Public-use data file and documentation. ftp://ftp.cdc.gov/pub/health_statistics/nchs/. 2020.
Haque RA, Usmani OS, Barnes PJ. Chronic idiopathic cough: a discrete clinical entity? Chest. 2005;127(5):1710-1713. https://doi.org/10.1378/chest.127.5.1710.
Paraskevas GK, Raikos A, Ioannidis O, Brand-Saberi B. Topographic anatomy of the internal laryngeal nerve: surgical considerations. Head Neck. 2012;34(4):534-540. https://doi.org/10.1002/hed.21769.
Dhillon VK. Superior laryngeal nerve block for neurogenic cough: a case series. Laryngoscope Investig Otolaryngol. 2019;4(4):410-413. https://doi.org/10.1002/lio2.292.
Altman KW, Noordzij JP, Rosen CA, Cohen S, Sulica L. Neurogenic cough. Laryngoscope. 2015;125(7):1675-1681. https://doi.org/10.1002/lary.25186.
Sulica L. The superior laryngeal nerve: function and dysfunction. Otolaryngol Clin N Am. 2004;37(1):183-201. https://doi.org/10.1016/S0030-6665(03)00175-0.
French CL, Irwin RS, Curley FJ, Krikorian CJ. Impact of chronic cough on quality of life. Arch Intern Med. 1998;158(15):1657. https://doi.org/10.1001/archinte.158.15.1657.
Hulme K, Deary V, Dogan S, Parker SM. Psychological profile of individuals presenting with chronic cough. ERJ Open Res. 2017;3(1):00099-2016. https://doi.org/10.1183/23120541.00099-2016.
Lee B, Woo P. Chronic cough as a sign of laryngeal sensory neuropathy: diagnosis and treatment. Ann Otol Rhinol Laryngol. 2005;114(4):253-257. https://doi.org/10.1177/000348940511400401.
Kuzniar TJ, Morgenthaler TI, Afessa B, Lim KG. Chronic cough from the patient's perspective. Mayo Clin Proc. 2007;82(1):56-60. https://doi.org/10.4065/82.1.56.
Giliberto JP, Cohen SM, Misono S. Are neuromodulating medications effective for the treatment of chronic neurogenic cough? Laryngoscope. 2017;127(5):1007-1008. https://doi.org/10.1002/lary.26393.
Dion GR, Teng SE, Achlatis E, Fang Y, Amin MR. Treatment of neurogenic cough with tramadol: a pilot study. Otolaryngol-Head Neck Surg. 2017;157(1):77-79. https://doi.org/10.1177/0194599817703949.
Ryan NM, Vertigan AE, Bone S, Gibson PG. Cough reflex sensitivity improves with speech language pathology management of refractory chronic cough. Cough. 2010;6:5. https://doi.org/10.1186/1745-9974-6-5.
Wamkpah NS, Peterson AM, Lee JJ, et al. Curbing the cough: multimodal treatments for neurogenic cough: a systematic review and meta-analysis. Laryngoscope Published online October 21. 2020;132(1):107-123. https://doi.org/10.1002/lary.29146.
Simpson CB, Tibbetts KM, Loochtan MJ, Dominguez LM. Treatment of chronic neurogenic cough with in-office superior laryngeal nerve block. Laryngoscope. 2018;128(8):1898-1903. https://doi.org/10.1002/lary.27201.
Duffy JR, Litts JK, Fink DS. Superior laryngeal nerve block for treatment of neurogenic cough. Laryngoscope. 2021;131(10):E2676-E2680. https://doi.org/10.1002/lary.29585.
Tipton CB, O'Rourke AK. Efficacy of superior laryngeal nerve block for the treatment of neurogenic cough: a retrospective review. Clin Otolaryngol. 2022;47(1):187-191. https://doi.org/10.1111/coa.13857.
Shembel AC, Rosen CA, Zullo TG, Gartner-Schmidt JL. Development and validation of the cough severity index: a severity index for chronic cough related to the upper airway. Laryngoscope. 2013;123(8):1931-1936. 10/1002/lary.23916.
Hull JH, Menon A. Laryngeal hypersensitivity in chronic cough. Pulm Pharmacol Ther. 2015;35:111-116. https://doi.org/10.1016/j.pupt.2015.08.008.
Bastian RW, Vaidya AM, Delsupehe KG. Sensory neuropathic cough: a common and treatable cause of chronic cough. Otolaryngol Head Neck Surg. 2006;135(1):17-21. https://doi.org/10.1016/j.otohns.2006.02.003.
Vertigan AE, Gibson PG. Chronic refractory cough as a sensory neuropathy: evidence from a reinterpretation of cough triggers. J Voice. 2011;25(5):596-601. https://doi.org/10.1016/j.jvoice.2010.07.009.
Latremoliere A, Woolf CJ. Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain. 2009;10(9):895-926. https://doi.org/10.1016/j.jpain.2009.06.012.
Dosenovic S, Jelicic Kadic A, Miljanovic M, et al. Interventions for neuropathic pain: an overview of systematic reviews. Anesth Analg. 2017;125(2):643-652. https://doi.org/10.1213/ANE.0000000000001998.
Eker HE, Cok OY, Aribogan A, Arslan G. Management of neuropathic pain with methylprednisolone at the site of nerve injury. Pain Med. 2012;13(3):443-451. https://doi.org/10.1111/j.1526-4637.2011.01323.x.
Joo JD, Choi JW, In JH, et al. Lidocaine suppresses the increased extracellular signal-regulated kinase/cyclic AMP response element-binding protein pathway and pro-inflammatory cytokines in a neuropathic pain model of rats. Eur J Anaesthesiol. 2011;28:106-111. https://doi.org/10.1097/eja.0b013e32834050fb.
Tipton, C. Efficacy of Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough: A Prospective, Placebo-Controlled Single-Blinded Trial. Oral presentation at: 2022 Fall Voice Conference; October, 2022; San Francisco, CA.
Hatcher, J. Virtual Interprofessional Chronic Cough Clinic: An Efficient and Appealing Approach to a Complex Problem. Oral Presentation at: 2022 Fall Voice Conference; October, 2022; San Francisco, CA.
Shin HW, Ju BJ, Jang YK, You HS, Kang H, Park JY. Effect of tramadol as an adjuvant to local anesthetics for brachial plexus block: a systematic review and meta-analysis. PLoS One. 2017;12(9):e0184649. https://doi.org/10.1371/journal.pone.0184649.
Heier C, Vallalar B, Butler K, Singaram C. Long-term efficacy of Abdominal Wall trigger point injections. S D Med. 2019;72(8):361-366. https://doi.org/10.1155/2005/274181.
Chamberlain Mitchell SAF, Garrod R, Clark L, et al. Physiotherapy, and speech and language therapy intervention for patients with refractory chronic cough: a multicentre randomised control trial. Thorax. 2017;72(2):129-136. https://doi.org/10.1136/thoraxjnl-2016-208843.
Speech Language Pathology Coverage. Accessed May 29, 2021. https://www.medicare.gov/coverage/speech-language-pathology-services
APP Pharmaceuticals, LLC. Xylocaine® (lidocaine HCl and epinephrine Injection, USP) [package insert]. U.S. Food and Drug Administration Website. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/006488s074lbl.pdf. Revised [02/2010]. Accessed June 3, 2021.
van Loghem JA, Fouché JJ, Thuis J. Sensitivity of aspiration as a safety test before injection of soft tissue fillers. J Cosmet Dermatol. 2018;17(1):39-46. https://doi.org/10.1111/jocd.12437.