ALSUntangled # 69: astaxanthin.

Humans Amyotrophic Lateral Sclerosis / drug therapy Complementary Therapies
Amyotrophic lateral sclerosis alternative therapy astaxanthin neurodegeneration oxidative stress

Journal

Amyotrophic lateral sclerosis & frontotemporal degeneration
ISSN: 2167-9223
Titre abrégé: Amyotroph Lateral Scler Frontotemporal Degener
Pays: England
ID NLM: 101587185

Informations de publication

Date de publication:
08 2023
Historique:
medline: 6 7 2023
pubmed: 26 1 2023
entrez: 25 1 2023
Statut: ppublish

Résumé

ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here we review astaxanthin which has plausible mechanisms for slowing ALS progression including antioxidant, anti-inflammatory, and anti-apoptotic effects. While there are no ALS-specific pre-clinical studies, one verified "ALS reversal" occurred in a person using a combination of alternative therapies which included astaxanthin. There have been no trials of astaxanthin in people living with ALS. Natural astaxanthin appears to be safe and inexpensive. Based on the above information, we support further pre-clinical and/or clinical trials of astaxanthin in disease models and PALS, respectively, to further elucidate efficacy.

Identifiants

DOI: 10.1080/21678421.2023.2171302 PMID: 36694292
pubmed: 36694292
doi: 10.1080/21678421.2023.2171302
doi:

Substances chimiques

astaxanthine 8XPW32PR7I

Types de publication

Review Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

553-557

Auteurs

Timothy Fullam (T)

Department of Neurology, UTSA, San Antonio, TX, USA.

Carmel Armon (C)

Department of Neurology, Loma Linda University, Loma Linda, CA, USA.

Paul Barkhaus (P)

Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.

Benjamin Barnes (B)

Department of Neurology, Medical College of Georgia, Augusta, GA, USA.

Morgan Beauchamp (M)

Neurosciences Clinical Trials Unit, UNC Chapel Hill, NC, USA.

Michael Benatar (M)

Department of Neurology, University of Miami, Miami, FL, USA.
ORCID: 0000-0003-4241-5135

Tulio Bertorini (T)

Neurology Department, University of Tennessee Health Science Center, Memphis, TN, USA.

Robert Bowser (R)

Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA.
ORCID: 0000-0001-5404-7259

Mark Bromberg (M)

Department of Neurology, University of Utah, Salt Lake City, UT, USA.

Javier Mascias Cadavid (J)

ALS Department, Hospital Carlos III-La Paz, Madrid, Spain.

Gregory T Carter (GT)

Department of Rehabilitation, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.

Mazen Dimachkie (M)

Department of Neurology, University of Kansas, Kansas City, KS, USA.

Dave Ennist (D)

Origent Data Sciences, Inc, Vienna, VA, USA.

Eva L Feldman (EL)

Department of Neurology, University of Michigan, Ann Arbor, MI, USA.

Terry Heiman-Patterson (T)

Department of Neurology, Temple Health, Philadelphia, PA, USA.

Sartaj Jhooty (S)

University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Isaac Lund (I)

Green Hope High School, Cary, NC, USA.

Christopher Mcdermott (C)

Department of Neuroscience, University of Sheffield, Sheffield, UK.
ORCID: 0000-0002-1269-9053

Gary Pattee (G)

Department of Neurology, University of Nebraska Medical Center, Omaha, NE, USA.

Dylan Ratner (D)

Tulane University, New Orleans, LA, USA.

Paul Wicks (P)

Independent Consultant, Lichfield, UK, and.
ORCID: 0000-0002-2293-9284

Richard Bedlack (R)

Department of Neurology, Duke University, Durham, NC, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › ALSUntangled # 69: astaxanthin.
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles de l'homéostasie des protéines › Protéinopathies TDP-43 › Sclérose latérale amyotrophique › ALSUntangled # 69: astaxanthin.
questionsmedicales.fr › Thérapeutique › Thérapies complémentaires › ALSUntangled # 69: astaxanthin.