Metaplastic breast cancer: A review.
Clinical management
Clinical outcomes
Epithelial-to-mesenchymal transition
Immunotherapy
Metaplastic breast cancer
Pathology
Targeted therapy
Journal
Critical reviews in oncology/hematology
ISSN: 1879-0461
Titre abrégé: Crit Rev Oncol Hematol
Pays: Netherlands
ID NLM: 8916049
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
received:
17
07
2022
revised:
19
12
2022
accepted:
20
01
2023
pubmed:
26
1
2023
medline:
8
2
2023
entrez:
25
1
2023
Statut:
ppublish
Résumé
Metaplastic breast cancer (MpBC) is an uncommon aggressive malignancy that is associated with a poor prognosis. Due to its rarity, the relationships between the clinical and pathological features of MpBC, treatment approach, and clinical outcomes remain underexplored. In the following review article, we synthesize the existing data on the clinical, pathological and genomic features, management, and outcomes of MpBC. We also identify potential targets for future clinical trials.
Identifiants
pubmed: 36696934
pii: S1040-8428(23)00012-4
doi: 10.1016/j.critrevonc.2023.103924
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
103924Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interest We declare no competing interests. B: CT chest with contrast (axial, left; coronal, right) of a second patient also depicts a large well-defined mass involving the pleura and minor fissure, with morphology similar to metastatic sarcomatous nodules.