Re-irradiation of recurrent vertebral metastasis after two previous spinal cord irradiation: A case report.
radiosurgery
retreatment
spine
stereotactic radiation
vertebral metastases
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2022
2022
Historique:
received:
26
07
2022
accepted:
09
12
2022
entrez:
26
1
2023
pubmed:
27
1
2023
medline:
27
1
2023
Statut:
epublish
Résumé
Management of a recurrent vertebral metastasis in a situation of previously irradiated spinal cord is a challenging clinical dilemma. We report a first case of second retreatment of a spinal metastasis initially irradiated with standard radiotherapy and stereotactic body radiation therapy (SBRT), who subsequently progressed with imaging-confirmed local tumor progression at the same level. After a third course of irradiation with SBRT, a complete response was achieved. After 8 months of follow-up, the patients remain free of local recurrence. A third course of vertebral irradiation for a recurrent vertebral metastasis failing to two previous irradiations, in this particular case, have shown the feasibility and efficacy of the technique as a salvage treatment option. This approach could be used in a selected group of patient if an adequate dose is delivered to the target while observing critical tissue tolerance limits.
Sections du résumé
Background
UNASSIGNED
Management of a recurrent vertebral metastasis in a situation of previously irradiated spinal cord is a challenging clinical dilemma.
Case presentation
UNASSIGNED
We report a first case of second retreatment of a spinal metastasis initially irradiated with standard radiotherapy and stereotactic body radiation therapy (SBRT), who subsequently progressed with imaging-confirmed local tumor progression at the same level. After a third course of irradiation with SBRT, a complete response was achieved. After 8 months of follow-up, the patients remain free of local recurrence.
Conclusion
UNASSIGNED
A third course of vertebral irradiation for a recurrent vertebral metastasis failing to two previous irradiations, in this particular case, have shown the feasibility and efficacy of the technique as a salvage treatment option. This approach could be used in a selected group of patient if an adequate dose is delivered to the target while observing critical tissue tolerance limits.
Identifiants
pubmed: 36698395
doi: 10.3389/fonc.2022.995376
pmc: PMC9869751
doi:
Types de publication
Case Reports
Langues
eng
Pagination
995376Commentaires et corrections
Type : ErratumIn
Informations de copyright
Copyright © 2023 Bentahila, Kinj, Huck, El Houat, Mampuya, Tuleasca, Ozsahin, Bourhis and Schiappacasse.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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