Comparison of Three β-Glucan Tests for the Diagnosis of Invasive Candidiasis in Intensive Care Units.
Candida
candidemia
intensive care
intra-abdominal candidiasis
Journal
Journal of clinical microbiology
ISSN: 1098-660X
Titre abrégé: J Clin Microbiol
Pays: United States
ID NLM: 7505564
Informations de publication
Date de publication:
22 02 2023
22 02 2023
Historique:
pubmed:
27
1
2023
medline:
3
3
2023
entrez:
26
1
2023
Statut:
ppublish
Résumé
The (1→3)-β-d-glucan (BDG) is a marker of invasive fungal infection that can be detected in serum by different commercial kits. In this study, we compared the performance of the Fungitell assay (FA), the Fungitell STAT assay (STAT), and the Wako β-glucan test (WA) for the diagnosis of invasive candidiasis (IC) in the intensive care unit (ICU). Patients for whom at least one BDG testing was required for a clinical suspicion of IC were retrospectively enrolled. A total of 85 serum samples from 56 patients were tested by the three BDG tests. The rate of IC was 23% (13/56) with a predominance of noncandidemic (intra-abdominal) IC. STAT and WA results exhibited overall good correlation with those obtained by FA (Spearman's coefficient
Identifiants
pubmed: 36700626
doi: 10.1128/jcm.01691-22
pmc: PMC9945570
doi:
Substances chimiques
beta-Glucans
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM