High-Risk Pulmonary Embolism During Labor:

CT, computed tomography CTA, computed tomography angiogram CTPA, computed tomography pulmonary angiography ECMO, extracorporeal membrane oxygenation HIT, heparin-induced thrombocytopenia LV, left ventricle PE, pulmonary embolism PVR, pulmonary vascular resistance RV, right ventricle SBP, systolic blood pressure TTE, transthoracic echocardiogram multimodality imaging pregnancy pulmonary embolism

Journal

JACC. Case reports
ISSN: 2666-0849
Titre abrégé: JACC Case Rep
Pays: Netherlands
ID NLM: 101757292

Informations de publication

Date de publication:
18 Jan 2023
Historique:
received: 07 09 2022
revised: 04 10 2022
accepted: 06 10 2022
entrez: 27 1 2023
pubmed: 28 1 2023
medline: 28 1 2023
Statut: epublish

Résumé

While in labor, a 37-year-old woman developed acute dyspnea, hypoxemia, and tachycardia. Transthoracic echocardiography demonstrated severe right ventricular dilation and dysfunction, raising the suspicion of acute pulmonary embolism. The patient indeed had bilateral pulmonary embolism, necessitating percutaneous thrombectomy. Her course was complicated by another saddle pulmonary embolus, heparin-induced thrombocytopenia, and COVID-19 infection. This clinical case illustrates the importance of prompt diagnosis of acute pulmonary embolism in a peripartum female patient, the multidisciplinary approach of management, and how to approach clinical complications such as heparin-induced thrombocytopenia. Furthermore, long-term management in acute pulmonary embolism is presented.

Identifiants

pubmed: 36704055
doi: 10.1016/j.jaccas.2022.10.001
pii: S2666-0849(22)00764-1
pmc: PMC9871077
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

101650

Informations de copyright

© 2023 by the American College of Cardiology Foundation. Published by Elsevier.

Déclaration de conflit d'intérêts

The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Références

J Intensive Care Med. 2021 Sep;36(9):1098-1109
pubmed: 33853435
Obstet Gynecol Surv. 1995 Jul;50(7):534-41
pubmed: 7566831
Crit Care Med. 2004 Apr;32(4):1035-40
pubmed: 15071398
Chest. 2015 Apr;147(4):1043-1062
pubmed: 25317677
Int J Obstet Anesth. 2019 Feb;37:118-121
pubmed: 30660373
Circulation. 2014 Jan 28;129(4):479-86
pubmed: 24226805
J Thromb Thrombolysis. 2020 Nov;50(4):929-941
pubmed: 32347509
N Engl J Med. 2021 Apr 29;384(17):1623-1634
pubmed: 33913639
Crit Care. 2017 Mar 28;21(1):76
pubmed: 28347320
Eur Heart J. 2022 Oct 11;43(38):3618-3731
pubmed: 36017548
Thromb Haemost. 2022 Oct;122(10):1779-1793
pubmed: 35472708
Front Cardiovasc Med. 2022 Mar 08;9:856594
pubmed: 35350540
Semin Ultrasound CT MR. 2022 Aug;43(4):333-343
pubmed: 35738818
Heart. 2019 Dec;105(23):1785-1792
pubmed: 31439657
J Thorac Imaging. 2023 Jan 1;38(1):23-28
pubmed: 36162078
JACC Cardiovasc Imaging. 2014 Jun;7(6):553-60
pubmed: 24412192
ESC Heart Fail. 2021 Oct;8(5):4318-4321
pubmed: 34431236
Eur Heart J. 2020 Jan 21;41(4):543-603
pubmed: 31504429
Eur Heart J Open. 2022 Feb 23;2(2):oeac007
pubmed: 35919120
Eur Heart J. 2018 Dec 14;39(47):4196-4204
pubmed: 30137303
J Am Soc Echocardiogr. 2018 May;31(5):527-550.e11
pubmed: 29573927
Chest. 2022 Jun;161(6):1628-1641
pubmed: 34914975
Obstet Gynecol Surv. 2022 Jul;77(7):433-444
pubmed: 35792687
Thromb Res. 2021 Aug;204:57-65
pubmed: 34146979
Chest. 2022 Jul 2;:
pubmed: 35792185
J Vasc Interv Radiol. 2015 Jul;26(7):992-1000
pubmed: 25899048
Respir Med Case Rep. 2021 Nov 10;34:101551
pubmed: 34868870
Ann Thorac Surg. 2004 Feb;77(2):694-5
pubmed: 14759462
Prog Cardiovasc Dis. 2012 Sep-Oct;55(2):187-98
pubmed: 23009915
J Am Heart Assoc. 2020 Jul 7;9(13):e016072
pubmed: 32578471
J Vasc Surg. 2014 Feb;59(2):456-64
pubmed: 23958068

Auteurs

Hooman Poor (H)

Division of Pulmonary, Critical Care, and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Gregory Serrao (G)

The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Julia Grapsa (J)

Department of Cardiovascular Sciences, Guys and St Thomas NHS Trust, Long, United Kingdom.

Y S Chandrashekhar (YS)

University of Minnesota, Minneapolis, Minnesota, USA.

Angela Bianco (A)

Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Robert A Lookstein (RA)

Department of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Valentin Fuster (V)

The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Classifications MeSH