No Increased Risk of Taking Additional Intestinal Mucosal Research Biopsies From the Duodenum During Pediatric Endoscopy.
Journal
Journal of pediatric gastroenterology and nutrition
ISSN: 1536-4801
Titre abrégé: J Pediatr Gastroenterol Nutr
Pays: United States
ID NLM: 8211545
Informations de publication
Date de publication:
01 04 2023
01 04 2023
Historique:
pmc-release:
01
04
2024
pubmed:
28
1
2023
medline:
25
3
2023
entrez:
27
1
2023
Statut:
ppublish
Résumé
Studies involving human intestinal tissue are essential for advancing the field of celiac disease (CeD), as diagnosis requires duodenal biopsies. Performing studies in children helps to better understand CeD in this important subpopulation. This study aims to determine the risk in obtaining duodenal research biopsies during pediatric endoscopy. In this retrospective chart review from 2016 to 2022 of 1180 research subjects and controls, there were 18 procedure-related adverse events within 48 hours. Most adverse events were for symptoms of pain and fever. There was no increased risk of adverse events if additional duodenal research biopsies were taken during pediatric endoscopy.
Identifiants
pubmed: 36705668
doi: 10.1097/MPG.0000000000003723
pii: 00005176-202304000-00017
pmc: PMC10038907
mid: NIHMS1868000
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
480-482Subventions
Organisme : NIDDK NIH HHS
ID : K23 DK122127
Pays : United States
Informations de copyright
Copyright © 2023 by European Society for European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
Déclaration de conflit d'intérêts
M.M.L. served on an advisory board for Mozart Therapeutics and 9Meters Biopharma and acted as a consultant for Anokion. She has served as site-PI for Takeda Pharmaceuticals. The remaining authors report no conflicts of interest.
Références
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