Assessment of immunological memory formation in vivo.

Mice Animals Immunologic Memory Immunotherapy Neoplasms / pathology
Immunogenic cell death Immunotherapy In vivo experimentation Sequential injections

Journal

Methods in cell biology
ISSN: 0091-679X
Titre abrégé: Methods Cell Biol
Pays: United States
ID NLM: 0373334

Informations de publication

Date de publication:
2023
Historique:
entrez: 29 1 2023
pubmed: 30 1 2023
medline: 1 2 2023
Statut: ppublish

Résumé

The reinstatement of cancer immunosurveillance during cancer therapy is the sole means of achieving long term success with durable disease control and sometimes even cure. Induction of immunogenic cell death (ICD) by pharmacological or physical interventions such as anthracycline-based chemotherapy or ionizing irradiation, respectively, is a potent strategy for triggering immunological memory in immunocompetent mice. Thus, mice that were cured from syngeneic transplanted cancers were able to reject the same tumor cells several weeks after the eradication of the initial tumor, contrasting with the fact that antigenically distinct cells readily formed tumors. Here, we show how to harness sequential injections of antigenically identical or distinct cancer cells in immunocompetent animals to evaluate the generation of immunological memory.

Identifiants

DOI: 10.1016/bs.mcb.2021.12.029 PMID: 36710052
pubmed: 36710052
pii: S0091-679X(21)00134-5
doi: 10.1016/bs.mcb.2021.12.029
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

65-73

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Shuai Zhang (S)

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM UMR1138, Centre de Recherche des Cordeliers, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Université Paris Sud, Paris Saclay, Faculty of Medicine, Kremlin Bicêtre, France; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Liwei Zhao (L)

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM UMR1138, Centre de Recherche des Cordeliers, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France.

Hui Chen (H)

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM UMR1138, Centre de Recherche des Cordeliers, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Université Paris Sud, Paris Saclay, Faculty of Medicine, Kremlin Bicêtre, France.

Guido Kroemer (G)

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM UMR1138, Centre de Recherche des Cordeliers, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden. Electronic address: kroemer@orange.fr.

Peng Liu (P)

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM UMR1138, Centre de Recherche des Cordeliers, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France. Electronic address: peng.liu@inserm.fr.

Oliver Kepp (O)

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM UMR1138, Centre de Recherche des Cordeliers, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France. Electronic address: captain.olsen@gmail.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Assessment of immunological memory formation in vivo.
questionsmedicales.fr › Eucaryotes › Animaux › Assessment of immunological memory formation in vivo.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Mémoire immunologique › Assessment of immunological memory formation in vivo.
questionsmedicales.fr › Thérapeutique › Biothérapie › Immunothérapie › Assessment of immunological memory formation in vivo.
questionsmedicales.fr › Tumeurs › Assessment of immunological memory formation in vivo.