Smartphone and wearable detected atrial arrhythmias in Older Adults: Results of a fully digital European Case finding study.

Atrial arrhythmia Consumer electronics Digital trial Early detection Elderly population

Journal

European heart journal. Digital health
ISSN: 2634-3916
Titre abrégé: Eur Heart J Digit Health
Pays: England
ID NLM: 101778323

Informations de publication

Date de publication:
Dec 2022
Historique:
received: 22 06 2022
revised: 24 10 2022
entrez: 30 1 2023
pubmed: 31 1 2023
medline: 31 1 2023
Statut: epublish

Résumé

Simplified detection of atrial arrhythmias via consumer-electronics would enable earlier therapy in at-risk populations. Whether this is feasible and effective in older populations is not known. The fully remote, investigator-initiated Remote, digitally supported consumer-electronics-based screening is feasible in older European adults and identifies atrial arrhythmias in 5% of participants within 4 weeks of monitoring (NCT04579159).

Identifiants

pubmed: 36710894
doi: 10.1093/ehjdh/ztac067
pii: ztac067
pmc: PMC9779806
doi:

Banques de données

ClinicalTrials.gov
['NCT04579159']

Types de publication

Journal Article

Langues

eng

Pagination

610-625

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.

Déclaration de conflit d'intérêts

Conflict of interest: L.F. has received institutional research grants and non-financial support from European Union, British Heart Foundation, Medical Research Council (UK), NIHR, German Centre for Cardiovascular Research (DZHK), several biomedical companies and previously DFG. The Institute of Cardiovascular Research, University of Birmingham, has received an Accelerator Award by the British Heart Foundation AA/18/2/34218. L.F. and P.K. are listed as inventor of two patents held by University of Birmingham (Atrial Fibrillation Therapy WO 2015140571, Markers for Atrial Fibrillation WO 2016012783). U.S. received consultancy fees or honoraria from Università della Svizzera Italiana (USI, Switzerland), Roche Diagnostics (Switzerland), EP Solutions Inc. (Switzerland), Johnson & Johnson Medical Limited, (UK). U.S. is co-founder and shareholder of YourRhythmics BV, a spin-off company of the University Maastricht. R.B.S. has received speaker fees from BMS/Pfizer. P.K. receives research support for basic, translational, and clinical research projects from European Union, British Heart Foundation, Leducq Foundation, Medical Research Council (UK), and German Centre for Cardiovascular Research (DZHK), from several drug and device companies active in atrial fibrillation, and has received honoraria from several such companies in the past, but not in the last three years. K.J. is the trial Steering Committee chair and member of several committees of NIHR funded studies (no honorarium) and sub-committee chair of the NIHR Programme Grants for Applied Health Research. T.H. is the founder and CEO of Preventicus. E.C. and D.H. received funding from Daiichi Sankyo Europe and study devices from Preventicus GmbH. D.C. has received consulting fees from Bayer, Boehringer Ingelheim, Daiichi Sankyo and Pfizer. JO received support for attending meetings and/or travel from the EHRA 2022 Educational Grand and financial support for abroad studies and research from the German Academic Scholarship Foundation. E.V. and A.Z. received institutional grants from AFNET and from Biotronik.

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Auteurs

L Fabritz (L)

University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20251 Hamburg, Germany.
Department of Cardiology, University Heart and Vascular Center Hamburg, Martinistr. 52, 20251 Hamburg, Germany.
DZHK German Center for Cardiovascular Research, partner site Hamburg/Luebeck/Kiel, Germany.
Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston Wolfson Drive, B15 2TT Birmingham, UK.
Atrial Fibrillation NETwork (AFNET), Mendelstr 11, 48149 Münster, Germany.

D L Connolly (DL)

Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston Wolfson Drive, B15 2TT Birmingham, UK.
Department of Cardiology and R&D, Birmingham City Hospital, Sandwell and West Birmingham Trust, Dudley Road, B18 7QH Birmingham, UK.

E Czarnecki (E)

Atrial Fibrillation NETwork (AFNET), Mendelstr 11, 48149 Münster, Germany.

D Dudek (D)

Jagiellonian University Medical College, Center for Digital Medicine and Robotics, Ul. Kopernika 7E, 33-332 Kraków, Poland.
Maria Cecilia Hospital, Via Corriera, 1, 48033 Cotignola RA, Italy.

E Guasch (E)

Institut Clínic Cardio-Vascular, Hospital Clínic, University of Barcelona, Carrer de Villaroel, 170, 08036 Barcelona, CA, Spain, Spain.
IDIBAPS, Rosselló 149-153, 08036 Barcelona, CA, Spain.
CIBERCV, Monforte de Lemos 3-5, Pabellon 11, Planta 0, 28029 Madrid, Spain.

D Haase (D)

Atrial Fibrillation NETwork (AFNET), Mendelstr 11, 48149 Münster, Germany.

T Huebner (T)

Preventicus GmbH, Ernst-Abbe-Straße 15, 07743 Jena, Germany.

A Zlahoda-Huzior (A)

Department of Measurement and Electronics, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, Poland.

K Jolly (K)

Institute of Applied Health Research, University of Birmingham, Edgbaston, B15 2TT Birmingham, UK.

P Kirchhof (P)

Department of Cardiology, University Heart and Vascular Center Hamburg, Martinistr. 52, 20251 Hamburg, Germany.
DZHK German Center for Cardiovascular Research, partner site Hamburg/Luebeck/Kiel, Germany.
Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston Wolfson Drive, B15 2TT Birmingham, UK.
Atrial Fibrillation NETwork (AFNET), Mendelstr 11, 48149 Münster, Germany.

J Obergassel (J)

University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20251 Hamburg, Germany.
Department of Cardiology, University Heart and Vascular Center Hamburg, Martinistr. 52, 20251 Hamburg, Germany.
DZHK German Center for Cardiovascular Research, partner site Hamburg/Luebeck/Kiel, Germany.

U Schotten (U)

Atrial Fibrillation NETwork (AFNET), Mendelstr 11, 48149 Münster, Germany.
Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center +, Debyelaan 25, 6229 HX, Maastricht, The Netherlands.

E Vettorazzi (E)

Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Christoph-Probst-Weg 1, 20246 Hamburg, Germany.

S J Winkelmann (SJ)

University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20251 Hamburg, Germany.
Department of Cardiology, University Heart and Vascular Center Hamburg, Martinistr. 52, 20251 Hamburg, Germany.

A Zapf (A)

Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Christoph-Probst-Weg 1, 20246 Hamburg, Germany.

R B Schnabel (RB)

Department of Cardiology, University Heart and Vascular Center Hamburg, Martinistr. 52, 20251 Hamburg, Germany.
DZHK German Center for Cardiovascular Research, partner site Hamburg/Luebeck/Kiel, Germany.
Atrial Fibrillation NETwork (AFNET), Mendelstr 11, 48149 Münster, Germany.

Classifications MeSH