Immunogenicity and protective efficacy of a pan-fungal vaccine in preclinical models of aspergillosis, candidiasis, and pneumocystosis.
Aspergillus
Candida
Pneumocystis
fungal vaccine
mycoses
Journal
PNAS nexus
ISSN: 2752-6542
Titre abrégé: PNAS Nexus
Pays: England
ID NLM: 9918367777906676
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
received:
27
06
2022
accepted:
28
10
2022
entrez:
30
1
2023
pubmed:
31
1
2023
medline:
31
1
2023
Statut:
epublish
Résumé
Invasive fungal infections cause over 1.5 million deaths worldwide. Despite increases in fungal infections as well as the numbers of individuals at risk, there are no clinically approved fungal vaccines. We produced a "pan-fungal" peptide, NXT-2, based on a previously identified vaccine candidate and homologous sequences from
Identifiants
pubmed: 36712332
doi: 10.1093/pnasnexus/pgac248
pii: pgac248
pmc: PMC9802316
doi:
Types de publication
Journal Article
Langues
eng
Pagination
pgac248Subventions
Organisme : NIH HHS
ID : K01 OD026569
Pays : United States
Informations de copyright
© The Author(s) 2022. Published by Oxford University Press on behalf of National Academy of Sciences.
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