Governing biotechnology to provide safety and security and address ethical, legal, and social implications.
ELSI
biotechnology
governance
policy
safety-by-design
synthetic biology
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2022
2022
Historique:
received:
23
09
2022
accepted:
27
12
2022
entrez:
30
1
2023
pubmed:
31
1
2023
medline:
31
1
2023
Statut:
epublish
Résumé
The field of biotechnology has produced a wide variety of materials and products which are rapidly entering the commercial marketplace. While many developments promise revolutionary benefits, some of them pose uncertain or largely untested risks and may spur debate, consternation, and outrage from individuals and groups who may be affected by their development and use. In this paper we show that the success of any advanced genetic development and usage requires that the creators establish technical soundness, ensure safety and security, and transparently represent the product's ethical, legal, and social implications (ELSI). We further identify how failures to address ELSI can manifest as significant roadblocks to product acceptance and adoption and advocate for use of the "safety-by-design" governance philosophy. This approach requires addressing risk
Identifiants
pubmed: 36712887
doi: 10.3389/fgene.2022.1052371
pii: 1052371
pmc: PMC9873990
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1052371Informations de copyright
Copyright © 2023 Trump, Cummings, Klasa, Galaitsi and Linkov.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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