Initiation and adherence to isoniazid preventive therapy in children under 5 years of age in Manhiça, Southern Mozambique.
Mozambique
adherence
isoniazid
pediatric
preventive therapy
tuberculosis
Journal
Journal of tropical pediatrics
ISSN: 1465-3664
Titre abrégé: J Trop Pediatr
Pays: England
ID NLM: 8010948
Informations de publication
Date de publication:
05 12 2022
05 12 2022
Historique:
entrez:
31
1
2023
pubmed:
1
2
2023
medline:
2
2
2023
Statut:
ppublish
Résumé
The WHO recommends preventive treatment for all pediatric contacts of a confirmed TB case, but coverage remains low in many high TB burden countries. We aimed to assess the coverage and adherence of the isoniazid preventive therapy (IPT) program among children under 5 years of age with household exposure to an adult pulmonary TB case in a rural district of Southern Mozambique. The estimated IPT coverage was 11.7%. A longer distance to the health center and lower age of the children hindered IPT initiation. Among patients who started IPT, 12/18 (69.9%) were adherent to the 6-month treatment.
Identifiants
pubmed: 36718019
pii: 7010560
doi: 10.1093/tropej/fmad009
pii:
doi:
Substances chimiques
Isoniazid
V83O1VOZ8L
Antitubercular Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© The Author(s) [2023]. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.