Human umbilical cord mesenchymal stem cells: Heralding an effective treatment against esophageal cancer?
esophageal cancer
mesenchymal stem cells
umbilical cord
Journal
Cell biology international
ISSN: 1095-8355
Titre abrégé: Cell Biol Int
Pays: England
ID NLM: 9307129
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
revised:
30
12
2022
received:
04
09
2022
accepted:
02
01
2023
pubmed:
1
2
2023
medline:
4
3
2023
entrez:
31
1
2023
Statut:
ppublish
Résumé
Esophageal cancer (EC), as one of the leading causes of cancer-associated mortality, influences a remarkable population of subjects globally and is histologically divided into two types, comprising esophageal adenocarcinoma (EAC) and esophageal squamous cell carcinoma (ESCC). Although several therapeutic approaches are present for EC, such as radiotherapy, chemotherapy, and surgery, these options have low success with serious side effects, for example, gastrointestinal toxicity, esophagitis, and pulmonary complications. Thus, utilizing an effective tool with low side effects is urgent. Newly, mesenchymal stem cells (MSCs) have received special interest for treating diverse diseases, such as cancer. Among different sources of MSCs, human umbilical cord MSCs have notable benefits, and reports expressed that they may be effective in EC treatment. For this purpose, in this review study, we aimed to summarize evidence regarding the effects of human umbilical cord MSCs on EC with a mechanistic insight.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
714-719Informations de copyright
© 2023 International Federation for Cell Biology.
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