Undetectable JC virus CSF PCR in patients with JC virus-induced progressive multifocal leukoencephalopathy.
BK virus
Brainstem
Cerebellum
JC virus
Posterior fossa
Progressive multifocal leukoencephalopathy
Journal
Journal of neurovirology
ISSN: 1538-2443
Titre abrégé: J Neurovirol
Pays: United States
ID NLM: 9508123
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
received:
07
10
2022
accepted:
05
01
2023
revised:
15
11
2022
medline:
13
4
2023
pubmed:
2
2
2023
entrez:
1
2
2023
Statut:
ppublish
Résumé
The diagnosis of progressive multifocal leukoencephalopathy (PML) is based on a combination of clinical, radiographic, and laboratory findings. However, negative JC polyomavirus (JCPyV) PCR in CSF does not always rule out JCPyV-related PML. In this narrative review, we sought to examine the characteristic of biopsy-proven PML in patients with undetectable JCPyV CSF PCR and provide alternative approaches in this scenario.
Identifiants
pubmed: 36723823
doi: 10.1007/s13365-023-01113-7
pii: 10.1007/s13365-023-01113-7
doi:
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
94-99Informations de copyright
© 2023. The Author(s) under exclusive licence to The Journal of NeuroVirology, Inc.
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