Medications for the treatment of obesity.

Humans Leptin / metabolism Obesity / drug therapy Hypothalamus / metabolism
GLP1 receptor agonists Glucagon intestinal peptide (GIP) Hypothalamus Leptin-melanocortin Leptin Suspensive pharmacotherapy

Journal

Journal of visceral surgery
ISSN: 1878-7886
Titre abrégé: J Visc Surg
Pays: France
ID NLM: 101532664

Informations de publication

Date de publication:
04 2023
Historique:
medline: 3 4 2023
pubmed: 2 2 2023
entrez: 1 2 2023
Statut: ppublish

Résumé

After several years with no real therapeutic alternatives, the management of obesity is entering a new era with the development of new surgical and endoscopic bariatric techniques, digital therapeutics and the arrival of new classes of drugs. New medication treatments aim to reduce food intake, targeting the hypothalamic regulation of food intake and satiety. The mechanism of their action remains poorly understood but, combines weight reduction and amelioration of cardiometabolic risk factors with a favorable benefit-risk balance and known side effects, mainly digestive. The future will tell us how these drugs will find their place in the management of this chronic disease that is obesity.

Identifiants

DOI: 10.1016/j.jviscsurg.2022.12.002 PMID: 36725455
pubmed: 36725455
pii: S1878-7886(22)00176-X
doi: 10.1016/j.jviscsurg.2022.12.002
pii:
doi:

Substances chimiques

Leptin 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

S12-S14

Informations de copyright

Copyright © 2022. Published by Elsevier Masson SAS.

Auteurs

C Carette (C)

Paris Cité University, Nutrition Department, Specialized Obesity Center, Georges Pompidou European Hospital, AP-HP, 20, rue Leblanc, Paris, France.

C Rives-Lange (C)

Paris Cité University, Nutrition Department, Specialized Obesity Center, Georges Pompidou European Hospital, AP-HP, 20, rue Leblanc, Paris, France.

S Czernichow (S)

Paris Cité University, Nutrition Department, Specialized Obesity Center, Georges Pompidou European Hospital, AP-HP, 20, rue Leblanc, Paris, France. Electronic address: sebastien.czernichow@aphp.fr.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Medications for the treatment of obesity.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Adipokines › Leptine › Medications for the treatment of obesity.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › Medications for the treatment of obesity.
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Diencéphale › Hypothalamus › Medications for the treatment of obesity.