HIV Viral Load Scale-up Among Children and Adolescents: Trends in Viral Load Suppression, Sample Type and Processing in 7 PEPFAR Countries, 2015-2018.
Journal
The Pediatric infectious disease journal
ISSN: 1532-0987
Titre abrégé: Pediatr Infect Dis J
Pays: United States
ID NLM: 8701858
Informations de publication
Date de publication:
01 04 2023
01 04 2023
Historique:
pubmed:
3
2
2023
medline:
14
3
2023
entrez:
2
2
2023
Statut:
ppublish
Résumé
HIV-positive children and adolescents face gaps in viral load (VL) testing. To understand trends in pediatric/adolescent VL testing, 7 countries collected data from Laboratory Information Management Systems. Results showed increasing proportion of VL tests done through dried blood spot (DBS) and decreased sample rejection rates for DBS compared with plasma, supporting use of DBS VL when skilled phlebotomy is unavailable.
Identifiants
pubmed: 36728122
doi: 10.1097/INF.0000000000003824
pii: 00006454-202304000-00007
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Journal Article
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
e102-e104Subventions
Organisme : PEPFAR
Pays : United States
Informations de copyright
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to disclose.
Références
AIDSinfo. UNAIDS 2022 estimates. Available at: aidsinfo.unaids.org . Accessed August 23, 2022.
Lecher SL, Fonjungo P, Ellenberger E, et al. HIV viral load monitoring among patients receiving antiretroviral therapy— eight sub-Saharan Africa countries, 2013-2018. MMWR Morb Mortal Wkly Rep. 2021;70:775–778.
US Presidents Emergency Plan for AIDS Relief (PEPFAR) 2022 Country and Regional Operational Plan (COP/ROP) guidance for all PEPFAR countries. Available at: https://www.state.gov/2022-country-operational-plan-guidance . Accessed July 7, 2022.
Bacha JM, Dlamini S, Anawabi F, et al. Achieving antiretroviral therapy uptake and viral suppression among children and adolescents living with HIV in the UNAIDS 90-90-90 era across six countries in Eastern and Southern Africa- lessons from the BIPAI network. JAIDS. 2022;90:300–308.
PEPFAR Panorama Spotlight. US Presidents Emergency Plan for AIDS Relief (PEPFAR). 2021. Available at: https://data.pepfar.gov/additionalData . Accessed October 6, 2021.
Arpadi SM, Shiau S, De Gusmao EP, et al. Routine viral load monitoring in HIV-infected infants and children in low- and middle-income countries: challenges and opportunities. J Int AIDS Soc. 2017;20:e25001.
Rutstein S, Golin C, Wheeler SB, et al. On the front line of HIV virological monitoring: barriers and facilitators from a provider perspective in resource-limited settings. AIDS Care. 2016;28:1–10.
World Health Organization. Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: recommendations for a public health approach. 2021. Available at: https://www.who.int/publications/i/item/9789240031593 . Accessed September 14, 2021.
Drain PK, Dorward J, Bender A, et al. Point-of-care HIV viral load testing: an essential tool for a sustainable global HIV/AIDS response. Clin Microbiol Rev. 2019;32:e00097.
Fadare O, Yakubu T, Emerenini F, et al. Sustaining early infant diagnosis of HIV during coronavirus disease 2019 pandemic: experience collecting dried blood spots samples at home from HIV-exposed infants in Nigeria. Pediatric Infect Dis J. 2021;40:e529–e530.