Compensatory mechanisms from different exercise intensities in type 2 diabetes: a secondary analysis of a 1-year randomized controlled trial.
Compensation
Diabetes mellitus
HIIT
NEAT
NEPA
Spontaneous activity
Journal
Acta diabetologica
ISSN: 1432-5233
Titre abrégé: Acta Diabetol
Pays: Germany
ID NLM: 9200299
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
received:
03
11
2022
accepted:
17
01
2023
medline:
3
4
2023
pubmed:
3
2
2023
entrez:
2
2
2023
Statut:
ppublish
Résumé
This investigation aimed to determine the effect of different intensities of training on non-exercise physical activity (NEPA) and estimated thermogenesis (NEAT) from a 1-year exercise randomized controlled trial (RCT) in individuals with type 2 diabetes mellitus (T2DM) on non-training days. Additionally, changes in NEPA and estimated NEAT in those who failed (low-responders) or succeeded (high-responders) in attaining exercise-derived clinically meaningful reductions in body weight (BW) and fat mass (FM) (i.e., 6% for FM and 3% for BW) was assessed. Individuals with T2DM (n = 80) were enrolled in a RCT with three groups: resistance training combined with moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT) and a control group. Of the 80 participants, 56 (completed data) were considered for this secondary analysis. NEPA and estimated NEAT were obtained by accelerometry and body composition through dual-energy X-ray absorptiometry. After adjustments, no time*group interactions were found for estimated NEAT in the MICT (β = - 5.33, p = 0.366) and HIIT (β = - 5.70, p = 0.283), as well as for NEPA in the MICT (β = - 452.83, p = 0.833) and HIIT (β = - 2770.76, p = 0.201), when compared to controls. No compensatory changes in NEPA and estimated NEAT were observed when considering both low-responders and high-responders to FM and BW when compared to controls. Both MICT and HIIT did not result in any compensatory changes in estimated NEAT and NEPA with the intervention on non-training days. Moreover, no changes in estimated NEAT and NEPA were found when categorizing our participants as low-responders and high-responders to FM and BW when compared to controls. Trial registration clinicaltrials.gov ID. NCT03144505.
Identifiants
pubmed: 36729308
doi: 10.1007/s00592-023-02038-7
pii: 10.1007/s00592-023-02038-7
pmc: PMC10063485
doi:
Banques de données
ClinicalTrials.gov
['NCT03144505']
Types de publication
Randomized Controlled Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
645-654Subventions
Organisme : Fundação para a Ciência e a Tecnologia
ID : UIDB/00447/2020
Organisme : Fundação para a Ciência e a Tecnologia
ID : SFRH/BD/149394/2019
Organisme : Fundação para a Ciência e a Tecnologia
ID : SFRH/BD/ 85742/2012
Organisme : Fundação para a Ciência e a Tecnologia
ID : SFRH/BPD/115977/2016
Organisme : Fundação para a Ciência e a Tecnologia
ID : 2020.07856.BD
Organisme : Fundação para a Ciência e a Tecnologia
ID : 2020
Informations de copyright
© 2023. The Author(s).
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