The sex life of male patients with cirrhosis and its organic factors: What we have got so far?


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2023
Historique:
received: 20 07 2022
accepted: 11 01 2023
entrez: 2 2 2023
pubmed: 3 2 2023
medline: 7 2 2023
Statut: epublish

Résumé

The purpose of this study was to examine the sex lives of male cirrhotic patients organic factors affect them. We did an observational study of 220 cirrhotic men's satisfaction with their sexual lives. Assessment of sex satisfaction was carried out using the New Sexual Satisfaction Scale. The frequency of intercourse and masturbation was estimated. Then, the levels of albumin, total bilirubin, vitamin D, and sex steroids were examined. Ascites and sarcopenia subgroups of our patients were stratified. Along with sex steroids, albumin, total bilirubin, and vitamin D all had an impact on how satisfying sex was (r = 0.22), (r = 0.24), and (r = -0.17) affected sex satisfaction. There were strong positive correlations between vitamin D (r = 0.33), albumin (r = 0.59), and free testosterone, along with a negative correlation between total bilirubin (r = -0.63) and free testosterone. An imbalance in sex steroid levels was observed, leading to decreased frequency of intercourse(p < 0.0001), weakened erections(p < 0.0001), and reduced quality of orgasm (p < 0.0001). Significant new sex behavior changes were found, such as an increase in masturbation. Physical limitations such as ascites and sarcopenia also impacted the decreasing sex life. The sex life of cirrhotic men is affected. The decrease in the frequency of intercourse and sexual satisfaction is noticeable in male patients and leads to increased masturbation. Free Testosterone, vitamin D, albumin, and bilirubin play role in their sex life. In addition, ascites and sarcopenia not only affect their sex life but also hamper the quality of their well-being.

Identifiants

pubmed: 36730272
doi: 10.1371/journal.pone.0280915
pii: PONE-D-22-20502
pmc: PMC9894452
doi:

Substances chimiques

Vitamin D 1406-16-2
Steroids 0

Banques de données

figshare
['10.6084/m9.figshare.21936498']

Types de publication

Observational Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0280915

Informations de copyright

Copyright: © 2023 Darmadi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Darmadi Darmadi (D)

Faculty of Medicine, Department of Internal Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Cennikon Pakpahan (C)

Faculty of Medicine, Andrology Study Program, Universitas Airlangga, Surabaya, Indonesia.
Faculty of Medicine, Department of Biomedical Sciences, Universitas Airlangga, Surabaya, Indonesia.

Riska Habriel Ruslie (RH)

Faculty of Medicine, Department of Child Health, Universitas Prima Indonesia, Medan, Indonesia.

Bella Amanda (B)

Faculty of Medicine, Andrology Study Program, Universitas Airlangga, Surabaya, Indonesia.
Faculty of Medicine, Department of Biomedical Sciences, Universitas Airlangga, Surabaya, Indonesia.

Raditya Ibrahim (R)

Faculty of Medicine, Andrology Study Program, Universitas Airlangga, Surabaya, Indonesia.

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Classifications MeSH