Role of Gut Microbiome in Atherosclerosis: Molecular and Therapeutic Aspects.
Atherosclerosis
dysbiosis
gut
inflammation
microbiome
treatment
Journal
Current cardiology reviews
ISSN: 1875-6557
Titre abrégé: Curr Cardiol Rev
Pays: United Arab Emirates
ID NLM: 101261935
Informations de publication
Date de publication:
2023
2023
Historique:
received:
26
06
2022
revised:
07
12
2022
accepted:
07
12
2022
pmc-release:
05
07
2024
medline:
11
7
2023
pubmed:
4
2
2023
entrez:
3
2
2023
Statut:
ppublish
Résumé
Atherosclerosis is one of the most relevant and prevalent cardiovascular diseases of our time. It is one of the pathological entities that increases the morbidity and mortality index in the adult population. Pathophysiological connections have been observed between atherosclerosis and the gut microbiome (GM), represented by a group of microorganisms that are present in the gut. These microorganisms are vital for metabolic homeostasis in humans. Recently, direct and indirect mechanisms through which GM can affect the development of atherosclerosis have been studied. This has led to research into the possible modulation of GM and metabolites as a new target in the prevention and treatment of atherosclerosis. The goal of this review is to analyze the physiopathological mechanisms linking GM and atherosclerosis that have been described so far. We also aim to summarize the recent studies that propose GM as a potential target in atherosclerosis management.
Identifiants
pubmed: 36733248
pii: CCR-EPUB-129265
doi: 10.2174/1573403X19666230202164524
pmc: PMC10494273
doi:
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e020223213408Informations de copyright
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
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