Inhibitory synapse dysfunction and epileptic susceptibility associated with KIF2A deletion in cortical interneurons.
epilepsy
inhibitory synapses
interneuron
microtubules
tangential migration
Journal
Frontiers in molecular neuroscience
ISSN: 1662-5099
Titre abrégé: Front Mol Neurosci
Pays: Switzerland
ID NLM: 101477914
Informations de publication
Date de publication:
2022
2022
Historique:
received:
29
11
2022
accepted:
30
12
2022
entrez:
3
2
2023
pubmed:
4
2
2023
medline:
4
2
2023
Statut:
epublish
Résumé
Malformation of cortical development (MCD) is a family of neurodevelopmental disorders, which usually manifest with intellectual disability and early-life epileptic seizures. Mutations in genes encoding microtubules (MT) and MT-associated proteins are one of the most frequent causes of MCD in humans. KIF2A is an atypical kinesin that depolymerizes MT in ATP-dependent manner and regulates MT dynamics. In humans, single
Identifiants
pubmed: 36733270
doi: 10.3389/fnmol.2022.1110986
pmc: PMC9887042
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1110986Informations de copyright
Copyright © 2023 Ruiz-Reig, García-Sánchez, Schakman, Gailly and Tissir.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Prog Neurobiol. 2022 Jan;208:102177
pubmed: 34582949
Brain. 2012 May;135(Pt 5):1348-69
pubmed: 22427329
Front Cell Neurosci. 2019 Jun 04;13:244
pubmed: 31213986
Annu Rev Cell Dev Biol. 2019 Oct 6;35:523-542
pubmed: 31283379
Neurogenetics. 2017 Apr;18(2):73-79
pubmed: 27747449
Elife. 2018 Jan 09;7:
pubmed: 29313800
Scientifica (Cairo). 2013;2013:393975
pubmed: 24278775
Neurobiol Dis. 2016 Aug;92(Pt A):18-45
pubmed: 26299390
Dev Biol. 2006 Sep 15;297(2):387-401
pubmed: 16790240
Semin Cell Dev Biol. 2018 Apr;76:86-100
pubmed: 28918121
Mol Genet Genomic Med. 2016 Sep 28;4(6):599-603
pubmed: 27896282
J Neurosci Methods. 1998 Jul 1;82(1):17-24
pubmed: 10223511
Curr Neuropharmacol. 2008 Mar;6(1):1-20
pubmed: 19305785
Cell. 2003 Jul 25;114(2):229-39
pubmed: 12887924
Nat Genet. 2013 Jun;45(6):639-47
pubmed: 23603762
J Vis Exp. 2018 Jun 12;(136):
pubmed: 29985308
Hum Mol Genet. 2020 Mar 27;29(5):766-784
pubmed: 31919497
Nat Commun. 2018 Jul 6;9(1):2628
pubmed: 29980677
Cereb Cortex. 2015 Sep;25(9):2939-50
pubmed: 24794919
Development. 2021 Feb 22;148(4):
pubmed: 33531432
Cell. 1999 Jan 8;96(1):69-78
pubmed: 9989498
Magn Reson Med. 2013 Jan;69(1):248-54
pubmed: 22442096
Neuron. 2013 Jan 9;77(1):70-82
pubmed: 23312517
Nat Genet. 2002 Nov;32(3):359-69
pubmed: 12379852
Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2209714119
pubmed: 36343267
J Neurosci. 2011 Mar 23;31(12):4650-62
pubmed: 21430164
Neuron. 2013 Jun 19;78(6):971-85
pubmed: 23791193
Prog Brain Res. 2016;226:81-126
pubmed: 27323940
Hum Mol Genet. 2018 Jan 15;27(2):224-238
pubmed: 29077851
Brain. 2009 Jun;132(Pt 6):1563-76
pubmed: 19439424
Cell Rep. 2013 Apr 25;3(4):971-7
pubmed: 23562155
Mol Syndromol. 2016 Sep;7(4):220-233
pubmed: 27781032
Neuroscience. 2019 Oct 15;418:291-310
pubmed: 31487502
Neuron. 2015 Dec 16;88(6):1208-1226
pubmed: 26671463
Am J Med Genet A. 2021 Apr;185(4):1113-1119
pubmed: 33506645
J Neurosci. 2003 Jan 1;23(1):167-74
pubmed: 12514213
Development. 2016 May 15;143(10):1753-65
pubmed: 27034423
Epilepsia Open. 2017 Sep;2(3):284-306
pubmed: 29062978
BMC Neurosci. 2016 Jun 10;17(1):35
pubmed: 27287386
Cereb Cortex. 2017 May 1;27(5):2841-2856
pubmed: 27178193