Transatlantic progress in measurement of cognitive outcomes in paediatric oncology trials.

brain tumour cancer child cognitive late effects paediatric quality of survival

Journal

Pediatric blood & cancer
ISSN: 1545-5017
Titre abrégé: Pediatr Blood Cancer
Pays: United States
ID NLM: 101186624

Informations de publication

Date de publication:
05 2023
Historique:
revised: 23 11 2022
received: 27 09 2021
accepted: 24 11 2022
pubmed: 4 2 2023
medline: 25 3 2023
entrez: 3 2 2023
Statut: ppublish

Résumé

The importance of measuring quality of survival within paediatric oncology trials is increasingly recognised. However, capturing neuropsychological outcomes and other aspects of quality of survival in the context of large or multinational trials can be challenging. We provide examples of protocols designed to address this challenge recently employed in clinical trials in the USA and Europe. We discuss their respective strengths and challenges, obstacles encountered and future opportunities for transatlantic collaboration.

Identifiants

pubmed: 36734371
doi: 10.1002/pbc.30171
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e30171

Informations de copyright

© 2023 The Authors. Pediatric Blood & Cancer published by Wiley Periodicals LLC.

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Auteurs

Sophie Thomas (S)

Department of Paediatric Neuropsychology, Nottingham Children's Hospital, Queen's Medical Centre, Nottingham, UK.
Child Brain Tumour Research Centre, School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK.

Leanne Embry (L)

Pediatric Hematology/Oncology, UT Health, San Antonio, Texas, USA.

Karin Walsh (K)

Division of Pediatric Neuropsychology, Children's National Hospital, Washington, DC, USA.
Departments of Psychiatry & Behavioral Medicine and Pediatrics, The George Washington University School of Medicine, Washington, DC, USA.

Kim Bull (K)

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, UK.

Richard Grundy (R)

Department of Paediatric Neuropsychology, Nottingham Children's Hospital, Queen's Medical Centre, Nottingham, UK.
Child Brain Tumour Research Centre, School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK.

Colin Kennedy (C)

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, UK.

Jurgen Lemiere (J)

Department Oncology, Pediatric Hemato-Oncology, KULeuven, University Hospital Leuven, Leuven, Belgium.

Pablo Hernáiz Driever (P)

Department of Pediatric Oncology and Hematology, Berlin Institute of Health, Charité-Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.

Jennifer Limond (J)

Department of Psychology, University of Exeter, Exeter, UK.

Mathilde Chevignard (M)

Rehabilitation Department for Children with Acquired Neurological Injury; and Outreach Team for Children and Adolescents with Acquired Brain Injury, Saint Maurice Hospitals, Saint Maurice, France.
Laboratoire d'Imagerie Biomédicale, LIB, Sorbonne Université, Paris, France.
GRC24, Handicap Moteur et Cognitif et Réadaptation (HaMCRe), Sorbonne Université, Paris, France.

Kristina Hardy (K)

Division of Pediatric Neuropsychology, Children's National Hospital, Washington, DC, USA.
Departments of Psychiatry & Behavioral Medicine and Pediatrics, The George Washington University School of Medicine, Washington, DC, USA.

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Classifications MeSH