Phenol-Croton Oil Chemical Peeling Induces Durable Improvement of Constitutional Periorbital Dark Circles.
Journal
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
ISSN: 1524-4725
Titre abrégé: Dermatol Surg
Pays: United States
ID NLM: 9504371
Informations de publication
Date de publication:
01 04 2023
01 04 2023
Historique:
medline:
17
4
2023
pubmed:
4
2
2023
entrez:
3
2
2023
Statut:
ppublish
Résumé
Constitutional periorbital dark circles (PDC) are common in skin of color and represent a therapeutic challenge. To summarize the experience of the International Peeling Society on the safety and effectiveness of deep chemical peeling in the treatment of constitutional PDC. Multi-institutional, retrospective case series (1990-2020) of constitutional PDC treated by deep chemical peeling. Descriptive analysis by age, sex, Fitzpatrick phototype, phenol-croton formula, degree and durability of improvement, and complications. Fifty-five phenol-croton oil peels were performed in 52 patients: 3 patients received a second peel for periorbital rhytids 72 to 84 months after the first peel. 92% (48/52) of patients were women; the median age was 46 years (range, 23-68 years). 89% (46/52) of patients were Fitzpatrick III-IV. Most common formula included phenol 60% to 65% and croton oil 0.6% to 0.7%. 89% (49/55) of peels demonstrated >50% clinical improvement. The median duration of improvement was 24 months (range, 1.5-168 months), and 69% (36/52) of patients demonstrated ongoing improvement at the last follow-up. 4% (2/55) of peels exhibited complications of persistent erythema that resolved without scarring. Based on its safety and effectiveness, deep chemical peels are a treatment of choice for constitutional PDC.
Sections du résumé
BACKGROUND
Constitutional periorbital dark circles (PDC) are common in skin of color and represent a therapeutic challenge.
OBJECTIVE
To summarize the experience of the International Peeling Society on the safety and effectiveness of deep chemical peeling in the treatment of constitutional PDC.
MATERIALS AND METHODS
Multi-institutional, retrospective case series (1990-2020) of constitutional PDC treated by deep chemical peeling. Descriptive analysis by age, sex, Fitzpatrick phototype, phenol-croton formula, degree and durability of improvement, and complications.
RESULTS
Fifty-five phenol-croton oil peels were performed in 52 patients: 3 patients received a second peel for periorbital rhytids 72 to 84 months after the first peel. 92% (48/52) of patients were women; the median age was 46 years (range, 23-68 years). 89% (46/52) of patients were Fitzpatrick III-IV. Most common formula included phenol 60% to 65% and croton oil 0.6% to 0.7%. 89% (49/55) of peels demonstrated >50% clinical improvement. The median duration of improvement was 24 months (range, 1.5-168 months), and 69% (36/52) of patients demonstrated ongoing improvement at the last follow-up. 4% (2/55) of peels exhibited complications of persistent erythema that resolved without scarring.
CONCLUSION
Based on its safety and effectiveness, deep chemical peels are a treatment of choice for constitutional PDC.
Identifiants
pubmed: 36735802
doi: 10.1097/DSS.0000000000003708
pii: 00042728-202304000-00010
doi:
Substances chimiques
Croton Oil
8001-28-3
carbol oil
0
Phenols
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
368-373Informations de copyright
Copyright © 2023 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
Références
Huang Y, Chang S, Ma L, Lee M, et al. Clinical analysis and classification of dark eye circle. Int J Dermatol 2014;53:164–70.
Ranu H, Thng S, Goh BK, Burger A, et al. Periorbital hyperpigmentation in Asians: an epidemiologic study and a proposed classification. Dermatol Surg 2011;37:1297–303.
Freitag F, Cestari T. What causes dark circles under the eyes? J Cosmet Dermatol 2007;6:211–5.
Nayak C, Giri A, Zambare U. A study of clinicopathological correlation of periorbital hyperpigmentation. Indian Dermatol Online J 2018;9:245–9.
Watanabe S, Nakai K, Ohnishi T. Condition known as “dark rings under the eyes” in the Japanese population is a kind of dermal melanocytosis which can be successfully treated by Q-switched ruby laser. Dermatol Surg 2006;32:785–9.
Wambier C, Lee K, Soon S, Sterling J, et al. Advanced chemical peels: phenol-croton oil peel. J Am Acad Dermatol 2019;81:327–36.
Kligman A, Baker T, Gordon H. Long-term histologic follow-up of phenol face peels. Plast Reconstr Surg. 1985;75:652–9.
Lee K, Sterling J, Wambier C, Soon SL, et al. Segmental phenol-croton oil chemical peels for periorbital and perioral rhytids. J Am Acad Dermatol 2019;81:e165–6.
Kurita M, Kato H, Yoshimura K. A therapeutic strategy based on histological assessment of hyperpigmented skin lesions in Asians. J Plast Reconstr Aesthet Surg 2009;62:955–63.
Graziosi A, Quaresma M, Michalany N, Ferreira L. Cutaneous idiopathic hyperchromia of the orbital region (cihor): a histopathological study. Aesth Plast Surg 2013;37:434–8.
Dayal S, Sahu P, Kumar Jain V, Khetri S, et al. Clinical efficacy and safety of 20% glycolic peel, 15% lactic peel, and topical 20% vitamin C in constitutional type of periorbital melanosis: a comparative study. J Cosmet Dermatol 2016;15:367–73.
Yamamoto Y, Yonei N, Kaminaka C, Kishioka A, et al. Effects of phenol peeling on dermal endothelial cells. J Dermatol Sci 2004;35:158–61.
Bertolini T, Giorgione J, Harvey D, Newton A. Protein kinase C translocation by modified phorbol esters with functionalized lipophilic regions. J Org Chem 2003;68:5028–36.
West T, Alster T. Improvement of infraorbital hyperpigmentation following carbon dioxide laser resurfacing. Dermatol Surg 1998;24:615–6.
Epstein J. Management of infraorbital dark circles: a significant cosmetic concern. Arch Facial Plast Surg 1999;1:303–7.