COVID-19 does not influence functional status after ARDS therapy.
Barthel index
COVID-19
Health-related quality of life
Viral pneumonia
Journal
Critical care (London, England)
ISSN: 1466-609X
Titre abrégé: Crit Care
Pays: England
ID NLM: 9801902
Informations de publication
Date de publication:
05 02 2023
05 02 2023
Historique:
received:
11
11
2022
accepted:
22
01
2023
entrez:
5
2
2023
pubmed:
6
2
2023
medline:
8
2
2023
Statut:
epublish
Résumé
Health-related quality of life after surviving acute respiratory distress syndrome has come into focus in recent years, especially during the coronavirus disease 2019 pandemic. A total of 144 patients with acute respiratory distress syndrome caused by COVID-19 or of other origin were recruited in a randomized multicenter trial. Clinical data during intensive care treatment and data up to 180 days after study inclusion were collected. Changes in the Sequential Organ Failure Assessment score were used to quantify disease severity. Disability was assessed using the Barthel index on days 1, 28, 90, and 180. Mortality rate and morbidity after 180 days were compared between patients with and without COVID-19. Independent risk factors associated with high disability were identified using a binary logistic regression. The SOFA score at day 5 was an independent risk factor for high disability in both groups, and score dynamic within the first 5 days significantly impacted disability in the non-COVID group. Mortality after 180 days and impairment measured by the Barthel index did not differ between patients with and without COVID-19. Resolution of organ dysfunction within the first 5 days significantly impacts long-term morbidity. Acute respiratory distress syndrome caused by COVID-19 was not associated with increased mortality or morbidity.
Identifiants
pubmed: 36740717
doi: 10.1186/s13054-023-04330-y
pii: 10.1186/s13054-023-04330-y
pmc: PMC9899507
doi:
Types de publication
Randomized Controlled Trial
Multicenter Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
48Subventions
Organisme : AKF Program of the University of Tuebingen
ID : 414-0-0
Organisme : Deutsche Forschungsgemeinschaft
ID : DFG-RO 3671/8-1
Informations de copyright
© 2023. The Author(s).
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