EAACI guidelines on environmental science in allergic diseases and asthma - Leveraging artificial intelligence and machine learning to develop a causality model in exposomics.


Journal

Allergy
ISSN: 1398-9995
Titre abrégé: Allergy
Pays: Denmark
ID NLM: 7804028

Informations de publication

Date de publication:
07 2023
Historique:
revised: 17 01 2023
received: 20 12 2022
accepted: 01 02 2023
medline: 3 7 2023
pubmed: 7 2 2023
entrez: 6 2 2023
Statut: ppublish

Résumé

Allergic diseases and asthma are intrinsically linked to the environment we live in and to patterns of exposure. The integrated approach to understanding the effects of exposures on the immune system includes the ongoing collection of large-scale and complex data. This requires sophisticated methods to take full advantage of what this data can offer. Here we discuss the progress and further promise of applying artificial intelligence and machine-learning approaches to help unlock the power of complex environmental data sets toward providing causality models of exposure and intervention. We discuss a range of relevant machine-learning paradigms and models including the way such models are trained and validated together with examples of machine learning applied to allergic disease in the context of specific environmental exposures as well as attempts to tie these environmental data streams to the full representative exposome. We also discuss the promise of artificial intelligence in personalized medicine and the methodological approaches to healthcare with the final AI to improve public health.

Identifiants

pubmed: 36740916
doi: 10.1111/all.15667
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1742-1757

Informations de copyright

© 2023 European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.

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Auteurs

Mohamed H Shamji (MH)

National Heart and Lung Institute, Imperial College London, London, UK.
NIHR Imperial Biomedical Research Centre, London, UK.

Markus Ollert (M)

Department of Infection and Immunity, Luxembourg Institute of Health (LIH), Esch-sur-Alzette, Luxembourg.
Department of Dermatology and Allergy Center, Odense Research Center for Anaphylaxis (ORCA), University of Southern Denmark, Odense, Denmark.

Ian M Adcock (IM)

National Heart and Lung Institute, Imperial College London, London, UK.
NIHR Imperial Biomedical Research Centre, London, UK.

Oscar Bennett (O)

Faculty Science Limited, London, UK.

Alberto Favaro (A)

Faculty Science Limited, London, UK.

Roudin Sarama (R)

National Heart and Lung Institute, Imperial College London, London, UK.
NIHR Imperial Biomedical Research Centre, London, UK.

Carmen Riggioni (C)

Pediatric Allergy and Clinical Immunology Service, Institut de Reserca Sant Joan de Deú, Barcelona, Spain.

Isabella Annesi-Maesano (I)

Research Director and Deputy DIrector of Institut Desbrest of Epidemiology and Public Health (IDESP) French NIH (INSERM) and University of Montpellier, Montpellier, France.

Adnan Custovic (A)

National Heart and Lung Institute, Imperial College London, London, UK.
NIHR Imperial Biomedical Research Centre, London, UK.

Sara Fontanella (S)

National Heart and Lung Institute, Imperial College London, London, UK.
NIHR Imperial Biomedical Research Centre, London, UK.

Claudia Traidl-Hoffmann (C)

Environmental Medicine Faculty of Medicine University of Augsburg, Augsburg, Germany.
CK-CARE, Christine Kühne Center for Allergy Research and Education, Davos, Switzerland.

Kari Nadeau (K)

Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, California, USA.

Lorenzo Cecchi (L)

SOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy.

Magdalena Zemelka-Wiacek (M)

Department of Clinical Immunology, Wroclaw Medical University, Wroclaw, Poland.

Cezmi A Akdis (CA)

Swiss Institute of Allergy and Asthma Research (SIAF), University Zurich, Davos, Switzerland.

Marek Jutel (M)

Department of Clinical Immunology, Wroclaw Medical University, Wroclaw, Poland.
ALL-MED Medical Research Institute, Wroclaw, Poland.

Ioana Agache (I)

Faculty of Medicine, Transylvania University, Brasov, Romania.

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