Sarcopenia in children with chronic liver disease: Prevalence and impact on liver transplant outcomes.
chronic liver disease
frailty
liver transplantation
pediatric patients
sarcopenia
Journal
Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492
Informations de publication
Date de publication:
2022
2022
Historique:
received:
31
08
2022
accepted:
28
09
2022
entrez:
6
2
2023
pubmed:
7
2
2023
medline:
7
2
2023
Statut:
epublish
Résumé
Sarcopenia is a clinical condition characterized by a reduction in muscle mass, which typically affects adult patients; however, it has recently been recognized in pediatric literature. Few studies in children with chronic liver disease (CLD) undergoing liver transplantation (LT) have investigated the role of sarcopenia, with controversial results. The aim of our study was to assess the prevalence and impact of sarcopenia among children with CLD who are candidates for LT. We conducted a retrospective, single-center study at Bambino Gesù Children's Hospital (Rome, Italy) from July 2016 to July 2021, evaluating all children (0-16 years old) with CLD listed for LT with an abdomen computed tomography imaging available before LT. The total psoas muscle surface area (t-PMSA) was defined as the sum of left and right psoas muscle surface area measured at L4-L5 on axial images. The t-PMSA
Identifiants
pubmed: 36741094
doi: 10.3389/fped.2022.1033570
pmc: PMC9891232
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1033570Informations de copyright
© 2022 Veraldi, Pietrobattista, Soglia, Monti, Alterio, Mosca, Liccardo, Basso, Della Corte, Russo, Candusso, Chiusolo, Tortora, Spada and Maggiore.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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