Transdural Skull Base Infiltration by Glioblastoma: Case Report and Review of the Literature.
Journal
Case reports in otolaryngology
ISSN: 2090-6765
Titre abrégé: Case Rep Otolaryngol
Pays: United States
ID NLM: 101576603
Informations de publication
Date de publication:
2023
2023
Historique:
received:
31
01
2022
revised:
22
09
2022
accepted:
10
12
2022
entrez:
6
2
2023
pubmed:
7
2
2023
medline:
7
2
2023
Statut:
epublish
Résumé
We report the rare occurrence of a temporal glioblastoma multiforme (GBM) showing transdural tumor extension into adjacent mastoid cells. As the dura mater provides a barrier to intraaxial tumors, GBM seldom penetrates into the skull base, even though it is a high-grade astrocytoma with a tendency to spread. Yet, some mechanisms of GBM-induced skull invasion have been identified, making this entity a very rare but nonetheless relevant differential diagnosis in otherwise ambiguous cases of an intracerebral tumor extending into the skull base. In addition, imaging markers that may assist in distinguishing extra- from intraaxial tumor infiltration of the temporal bone are described.
Identifiants
pubmed: 36742066
doi: 10.1155/2023/4727288
pmc: PMC9891834
doi:
Types de publication
Case Reports
Langues
eng
Pagination
4727288Informations de copyright
Copyright © 2023 Michael Thrull et al.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest.
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