Study of Serum Zinc and Copper Levels and Tumor Pathology: A Pilot Study in People Affected with Head and Neck Cancers.
Copper
Copper/ Zinc ratio
Head and neck cancer
Zinc
Journal
Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
ISSN: 2231-3796
Titre abrégé: Indian J Otolaryngol Head Neck Surg
Pays: India
ID NLM: 9422551
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
03
04
2021
accepted:
26
04
2021
entrez:
6
2
2023
pubmed:
7
2
2023
medline:
7
2
2023
Statut:
ppublish
Résumé
This study aimed to determine understanding the role of serum copper, zinc and copper/zinc ratio with tumor staging in people newly diagnosed to be affected with Head and Neck cancer and by comparing with age matched health individuals devoid of any orodental maladies. The study included patients confirmed to be affected with HN cancer with histological diagnosis of Head and Neck cancer (60) and age matched healthy volunteers (N = 23). The demographic details like age, domicile, menopausal status and pathological details (like tumor stage, number of lymph node involvement, tumor size) were collected from the patient's hospital data file. The serum levels of zinc and copper assayed as per standard procedures and the zinc/copper was calculated for the cancer patients and controls. The data were subjected to unpaired "t" test and ANOVA with Bonferroni's multiple comparisons. The association between zinc and copper levels with pathological details between the variables was ascertained using the Pearson correlation coefficient(r). A statistical value of
Identifiants
pubmed: 36742902
doi: 10.1007/s12070-021-02589-7
pii: 2589
pmc: PMC9895224
doi:
Types de publication
Journal Article
Langues
eng
Pagination
6007-6015Informations de copyright
© Association of Otolaryngologists of India 2021.
Déclaration de conflit d'intérêts
Conflict of interestThe authors declare that they do not have any conflict of interest regarding the study topic.
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