Case report: Flexor carpi ulnaris tendinopathy in a lure-coursing dog treated with three platelet-rich plasma and platelet lysate injections.

canine orthopedics dog platelet lysate (PL) platelet-rich plasma (PRP) regenerative medicine tissue regeneration

Journal

Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658

Informations de publication

Date de publication:
2023
Historique:
received: 26 07 2022
accepted: 05 01 2023
entrez: 6 2 2023
pubmed: 7 2 2023
medline: 7 2 2023
Statut: epublish

Résumé

In the present case report a 7-year-old male Whippet competing in lure-coursing presented with third-degree recurrent lameness of the right forelimb, pain on palpation of the caudal aspect of the carpus and swelling of the forearm proximally to the accessory carpal bone. Clinical, radiographic, and ultrasonographic evaluation diagnosed a flexor carpi ulnaris (FCU) chronic tendinopathy unresponsive to previously attempted conservative treatments such as oral non-steroidal anti-inflammatory drugs (NSAIDs) administration along with padded palmar splint application and rest. The dog was subjected to one injection of autologous platelet-rich plasma (PRP) obtained using a double centrifugation tube method, followed by two platelet lysate (PL) injections. Treatment was administered at three-week intervals. The healing process was assessed through clinical and ultrasonographic imaging (US) on the day of the first injection (T0), and at week three (T1), six (T2), twelve (T3), fifty-two (T4), and one-hundred-and-four (T5). Fiber alignment score (FAS) and echogenicity score (ES) were developed by modifying a previously published US assessment scale. At T1, ES, and FAS improvement was detected, and at T2, further improvements in ES and FAS were observed. Ultrasonographic results were clinically consistent with the improvement in lameness: lameness grade 3/4 was detected at T0 and grade 2/4 at T1. A lameness grade of 1/4 was detected at T2, and grade 0/4 was observed at T3, T4, and T5. Moreover, at T5, the dog returned to competition, and no history of re-injury was reported. Our results suggest that the treatment of FCU tendinopathy in lure-coursing dogs with a combination of consecutive injections of autologous PRP and PL could be feasible. Additionally, no adverse reactions were observed.

Identifiants

pubmed: 36742986
doi: 10.3389/fvets.2023.1003993
pmc: PMC9893791
doi:

Types de publication

Case Reports

Langues

eng

Pagination

1003993

Informations de copyright

Copyright © 2023 Franini, Entani, Colosio, Melotti and Patruno.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Alessio Franini (A)

Sporty Dog Veterinary Clinic, Brescia, Italy.

Maria Grazia Entani (MG)

Sporty Dog Veterinary Clinic, Brescia, Italy.

Elisa Colosio (E)

Sporty Dog Veterinary Clinic, Brescia, Italy.

Luca Melotti (L)

Department of Comparative Biomedicine and Food Science, University of Padua, Padua, Italy.

Marco Patruno (M)

Department of Comparative Biomedicine and Food Science, University of Padua, Padua, Italy.

Classifications MeSH