PSC-derived intestinal organoids with apical-out orientation as a tool to study nutrient uptake, drug absorption and metabolism.

barrier integrity drug discovery epithelial polarity gastrointestinal model intestinal organoids nutrient uptake

Journal

Frontiers in molecular biosciences
ISSN: 2296-889X
Titre abrégé: Front Mol Biosci
Pays: Switzerland
ID NLM: 101653173

Informations de publication

Date de publication:
2023
Historique:
received: 21 11 2022
accepted: 09 01 2023
entrez: 6 2 2023
pubmed: 7 2 2023
medline: 7 2 2023
Statut: epublish

Résumé

Intestinal organoids recapitulate many features of the

Identifiants

pubmed: 36743212
doi: 10.3389/fmolb.2023.1102209
pii: 1102209
pmc: PMC9889654
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1102209

Informations de copyright

Copyright © 2023 Kakni, López-Iglesias, Truckenmüller, Habibović and Giselbrecht.

Déclaration de conflit d'intérêts

RT and SG are founders and shareholders of 300MICRONS GmbH. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Panagiota Kakni (P)

MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Instructive Biomaterials Engineering, Maastricht University, Maastricht, Netherlands.

Carmen López-Iglesias (C)

Microscopy CORE lab, Maastricht Multimodal Molecular Imaging Institute (M4I), Maastricht University, Maastricht, Netherlands.

Roman Truckenmüller (R)

MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Instructive Biomaterials Engineering, Maastricht University, Maastricht, Netherlands.

Pamela Habibović (P)

MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Instructive Biomaterials Engineering, Maastricht University, Maastricht, Netherlands.

Stefan Giselbrecht (S)

MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Instructive Biomaterials Engineering, Maastricht University, Maastricht, Netherlands.

Classifications MeSH