Visceral to subcutaneous fat ratio predicts short-term mortality in patients with Covid 19. A multicenter study.


Journal

The British journal of radiology
ISSN: 1748-880X
Titre abrégé: Br J Radiol
Pays: England
ID NLM: 0373125

Informations de publication

Date de publication:
01 Mar 2023
Historique:
pubmed: 7 2 2023
medline: 23 3 2023
entrez: 6 2 2023
Statut: ppublish

Résumé

To evaluate the association of body composition parameters with outcomes in Covid-19. 173 patients hospitalized for Covid-19 infection in 6 European centers were included in this retrospective study. Measurements were performed at L3-level and comprised skeletal muscle index (SMI), muscle density (MD), and adipose tissue measurements [visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), intramuscular adipose tissue (IMAT), visceral-to-subcutaneous-adipose-tissue-area-ratio (VSR)]. The association with mortality, the need for intubation (MV), and the need for admission to ICU within 30 days were evaluated. Higher SAT density was associated with a greater risk of MV (OR = 1.071, 95%CI=(1.034;1.110), In patients hospitalized for Covid-19 infection, higher VSR seems to be a strong prognostic factor of short-term mortality. Weak associations with clinical course were found for MD and adipose tissue measurements. Male sex was the strongest prognostic factor of adverse clinical course. VSR is a prognostic biomarker for 30-day mortality in patients hospitalized for Covid-19 disease.

Identifiants

pubmed: 36744766
doi: 10.1259/bjr.20220869
pmc: PMC10078869
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

20220869

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Auteurs

Alexey Surov (A)

Department of Radiology,, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, Bochum, Germany.

Maximilian Thormann (M)

Clinic for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.

Hakan Kardas (H)

Clinic for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.

Mattes Hinnerichs (M)

Clinic for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.

Jazan Omari (J)

Clinic for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.

Eda Cingöz (E)

Istanbul Medical Faculty Radiology Department, Istanbul University, Istanbul, Turkey.

Mehmet Cingöz (M)

Department of Radiology, Istanbul Cam and Sakura City Hospital, Istanbul, Turkey.

Memduh Dursun (M)

Istanbul Medical Faculty Radiology Department, Istanbul University, Istanbul, Turkey.

İnan Kormaz (İ)

Department of Radiology, Hatay Mustafa Kemal University, Antakya, Hatay, Turkey.

Çağrı Orhan (Ç)

Department of Radiology, Hatay Mustafa Kemal University, Antakya, Hatay, Turkey.

Ömer Yıldız (Ö)

Radiology Department, University of Health Sciences, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Bakirkoy, Istanbul, Turkey.

Elif Hocaoğlu (E)

Radiology Department, University of Health Sciences, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Bakirkoy, Istanbul, Turkey.

Ercan Inci (E)

Radiology Department, University of Health Sciences, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Bakirkoy, Istanbul, Turkey.

Hakan Önder (H)

Radiology Department, Health Science University, Prof. Dr. Cemil Tascioğlu City Hospital, Istanbul, Turkey.

Hamdullah Erk (H)

Radiology Department, Health Science University, Prof. Dr. Cemil Tascioğlu City Hospital, Istanbul, Turkey.

Ougkour Chousein (O)

Department of Radiology, Tekirdag Namik Kemal University, Tekirdag, Turkey.

Hadi Sasani (H)

Department of Radiology, Tekirdag Namik Kemal University, Tekirdag, Turkey.

Korcan Aysun Gönen (KA)

Department of Radiology, Tekirdag Namik Kemal University, Tekirdag, Turkey.

Maciej Pech (M)

Clinic for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.

Andreas Wienke (A)

Institute of Medical Epidemiology, Biometry, and Informatics, Martin- Luther- University, Halle-Wittenberg, Germany.

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