The REPAIR Project, a Deep-Underground Radiobiology Experiment Investigating the Biological Effects of Natural Background Radiation: The First 6 Years.


Journal

Radiation research
ISSN: 1938-5404
Titre abrégé: Radiat Res
Pays: United States
ID NLM: 0401245

Informations de publication

Date de publication:
01 03 2023
Historique:
received: 14 11 2022
accepted: 17 01 2023
pubmed: 7 2 2023
medline: 11 3 2023
entrez: 6 2 2023
Statut: ppublish

Résumé

In 2017, a special edition of Radiation Research was published [Oct; Vol. 188 4.2 (https://bioone.org/journals/radiation-research/volume-188/issue-4.2)] which focused on a recently established radiobiology project within SNOLAB, a unique deep-underground research facility. This special edition included original articles, reviews and commentaries relevant to the research goals of this new project which was titled Researching the Effects of the Presence and Absence of Ionizing Radiation (REPAIR). These research goals were founded in understanding the biological effects of terrestrial and cosmic natural background radiation (NBR). Since 2017, REPAIR has evolved into a sub-NBR radiobiology research program which investigates these effects using multiple model systems and various biological endpoints. This paper summarizes the evolution of the REPAIR project over the first 6-years including its experimental scope and capabilities as well as research accomplishments.

Identifiants

pubmed: 36745561
pii: 490658
doi: 10.1667/RADE-22-00193.1
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

290-293

Informations de copyright

©2023 by Radiation Research Society. All rights of reproduction in any form reserved.

Auteurs

Jake Pirkkanen (J)

School of Natural Sciences, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada.

Christine Lalonde (C)

School of Natural Sciences, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada.

Michel Lapointe (M)

School of Natural Sciences, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada.

Taylor Laframboise (T)

School of Natural Sciences, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada.

Marc S Mendonca (MS)

Department of Radiation Oncology, Radiation and Cancer Biology Laboratories, and Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202.

Douglas R Boreham (DR)

School of Natural Sciences, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada.
Medical Sciences Division, Northern Ontario School of Medicine (NOSM University), Sudbury, Ontario, P3E 2C6, Canada.
Nuclear Innovation Institute, Port Elgin, Ontario, N0H 2C0, Canada.

Sujeenthar Tharmalingam (S)

School of Natural Sciences, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada.
Medical Sciences Division, Northern Ontario School of Medicine (NOSM University), Sudbury, Ontario, P3E 2C6, Canada.
Nuclear Innovation Institute, Port Elgin, Ontario, N0H 2C0, Canada.

Christopher Thome (C)

School of Natural Sciences, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada.
Medical Sciences Division, Northern Ontario School of Medicine (NOSM University), Sudbury, Ontario, P3E 2C6, Canada.
Nuclear Innovation Institute, Port Elgin, Ontario, N0H 2C0, Canada.

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Classifications MeSH