Synthesis of Bis(functionalized) Aminals via Successive Nucleophilic Amidation and Amination.

Journal

The Journal of organic chemistry
ISSN: 1520-6904
Titre abrégé: J Org Chem
Pays: United States
ID NLM: 2985193R

Informations de publication

Date de publication:
17 Feb 2023
Historique:
pubmed: 7 2 2023
medline: 7 2 2023
entrez: 6 2 2023
Statut: ppublish

Résumé

The central carbonyl group of diethyl mesoxalate (DEMO) exhibits high electrophilicity that allows it to be attacked by versatile nucleophiles. Even a less nucleophilic acid amide serves as a nucleophile to produce

Identifiants

DOI: 10.1021/acs.joc.2c02647 PMID: 36745736
pubmed: 36745736
doi: 10.1021/acs.joc.2c02647
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2207-2213

Auteurs

Kento Iwai (K)

School of Engineering Science, Kochi University of Technology, Tosayamada, Kami 782-8502, Kochi, Japan.
Research Center for Molecular Design, Kochi University of Technology, Tosayamada, Kami 782-8502, Kochi, Japan.
ORCID: 0000-0002-0923-604X

Akari Hikasa (A)

School of Engineering Science, Kochi University of Technology, Tosayamada, Kami 782-8502, Kochi, Japan.

Kotaro Yoshioka (K)

Kumiai Chemical Industry Co. Ltd., Nakanogo, Fuji 421-3306, Shizuoka, Japan.

Shinki Tani (S)

Kumiai Chemical Industry Co. Ltd., Nakanogo, Fuji 421-3306, Shizuoka, Japan.

Kazuto Umezu (K)

Kumiai Chemical Industry Co. Ltd., Nakanogo, Fuji 421-3306, Shizuoka, Japan.

Nagatoshi Nishiwaki (N)

School of Engineering Science, Kochi University of Technology, Tosayamada, Kami 782-8502, Kochi, Japan.
Research Center for Molecular Design, Kochi University of Technology, Tosayamada, Kami 782-8502, Kochi, Japan.
ORCID: 0000-0002-6052-8697

Classifications MeSH