Predictive Value of Red Cell Distribution Width in the Diagnosis of Peripherally Inserted Central Catheter (PICC)-Related Thrombosis Among Cancer Patients.
PICC-related thrombosis
cancer patients
red cell distribution width
smoking history
Journal
International journal of general medicine
ISSN: 1178-7074
Titre abrégé: Int J Gen Med
Pays: New Zealand
ID NLM: 101515487
Informations de publication
Date de publication:
2023
2023
Historique:
received:
01
11
2022
accepted:
17
01
2023
entrez:
7
2
2023
pubmed:
8
2
2023
medline:
8
2
2023
Statut:
epublish
Résumé
This study aimed to investigate the predictive value of red cell distribution width (RDW) in patients with peripherally inserted central catheter (PICC)-related thrombosis. This was a case‒control study. A total of 98 cancer patients undergoing PICC placement from January 2017 to December 2019 at the ICU Venous Access Center of Peking University Cancer Hospital were retrospectively analyzed. These included 47 cases in the thrombosis group and 51 cases in the nonthrombosis group according to the occurrence of PICC-related thrombosis within 90 days after the PICC procedure. a) RDW was significantly higher in the thrombosis group (15.98±1.93) than in the nonthrombosis group (13.98±1.09). Additionally, the number of smoking histories in the thrombosis group (18, 38.30%) was significantly higher than that in the nonthrombosis group (5, 9.80%). b) Logistic regression analysis indicated that RDW and smoking history were independent risk factors for PICC-related thrombosis (OR: 3.028, P<0.001; OR: 5.640, P=0.023). c) The area under the receiver operating characteristic (ROC) curve of the combination of RDW and smoking history was 86.8%, and the sensitivity and specificity for predicting thrombosis after PICC were 85.1% and 80%, respectively. d) Cox regression analysis revealed that RDW and smoking history were independent risk factors for PICC-related thrombosis (p<0.001). e) Results from Kaplan‒Meier analysis showed that incidence of PICC-related thrombosis in patients with RDW less than 14.75% is significantly lower than those with RDW 14.75% and above (p<0.001). e) Baseline RDW was not different between the two groups (P>0.05), ΔRDW was significantly different between the two groups (p<0.001). The combined use of RDW and smoking history has early evaluation and predictive value in the diagnosis of PICC-related thrombosis.
Identifiants
pubmed: 36747971
doi: 10.2147/IJGM.S395745
pii: 395745
pmc: PMC9899010
doi:
Types de publication
Journal Article
Langues
eng
Pagination
359-365Informations de copyright
© 2023 Zhai et al.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to declare for this work.
Références
Thromb J. 2019 Jan 25;17:2
pubmed: 30697126
Clin Biochem. 2020 Mar;77:1-6
pubmed: 31935355
J Cancer. 2019 Jul 10;10(18):4305-4317
pubmed: 31413750
JAMA Intern Med. 2015 Jul;175(7):1226-7
pubmed: 25961734
Dis Markers. 2017;2017:3041565
pubmed: 29109595
Crit Rev Clin Lab Sci. 2015;52(2):86-105
pubmed: 25535770
Clin Hemorheol Microcirc. 2011;49(1-4):463-72
pubmed: 22214717
Chest. 2011 Jul;140(1):48-53
pubmed: 21349931
PLoS Med. 2013;10(9):e1001515
pubmed: 24068896
Turk J Anaesthesiol Reanim. 2020 Feb;48(1):11-16
pubmed: 32076674
Oncotarget. 2017 Feb 28;8(9):16027-16035
pubmed: 27926498
Int Angiol. 2017 Aug;36(4):295-298
pubmed: 28263045
Biomark Med. 2020 Sep;14(13):1289-1298
pubmed: 33021384
Cleve Clin J Med. 2019 Mar;86(3):167-172
pubmed: 30849034
Dis Markers. 2015;2015:824624
pubmed: 26379362
Arch Pathol Lab Med. 2009 Apr;133(4):628-32
pubmed: 19391664
J Thromb Haemost. 2020 May;18(5):1009-1019
pubmed: 32020753
Clin Hemorheol Microcirc. 2013;53(1-2):131-41
pubmed: 22954636
J Thromb Thrombolysis. 2017 Oct;44(3):377-385
pubmed: 28730407
Eur Heart J. 2020 Nov 1;41(41):4057-4070
pubmed: 32585699
J Card Fail. 2011 Aug;17(8):626-33
pubmed: 21807323
Clin Respir J. 2020 Oct;14(10):901-907
pubmed: 32568446
Atherosclerosis. 2012 Sep;224(1):143-9
pubmed: 22748279
Front Pediatr. 2018 May 23;6:142
pubmed: 29876337