The molecular pathogenesis of craniopharyngiomas.


Journal

Archives of endocrinology and metabolism
ISSN: 2359-4292
Titre abrégé: Arch Endocrinol Metab
Pays: Brazil
ID NLM: 101652058

Informations de publication

Date de publication:
10 Mar 2023
Historique:
pubmed: 8 2 2023
medline: 16 3 2023
entrez: 7 2 2023
Statut: ppublish

Résumé

Research from the last 20 years has provided important insights into the molecular pathogenesis of craniopharyngiomas (CPs). Besides the well-known clinical and histological differences between the subtypes of CPs, adamantinomatous (ACP) and papillary (PCP) craniopharyngiomas, other molecular differences have been identified, further elucidating pathways related to the origin and development of such tumors. The present minireview assesses current knowledge on embryogenesis and the genetic, epigenetic, transcriptomic, and signaling pathways involved in the ACP and PCP subtypes, revealing the similarities and differences in their profiles. ACP and PCP subtypes can be identified by the presence of mutations in

Identifiants

pubmed: 36748936
pii: 2359-3997000000600
doi: 10.20945/2359-3997000000600
pmc: PMC10689043
doi:
pii:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

266-275

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Auteurs

Marina Lanciotti Campanini (ML)

Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil, mlanciotti@gmail.com.

João Paulo Almeida (JP)

Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, United States.

Clarissa Silva Martins (CS)

Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil.
Faculdade de Medicina, Universidade Federal do Mato Grosso do Sul, Campo Grande, RS, Brasil.

Margaret de Castro (M)

Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil.

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Classifications MeSH