Host-Microbiota Communication in Spontaneously Hypertensive Rats Generates Unique IgA-Coated Gut Microbes.
Immunoglobin A‐coated bacteria
host‐microbiota communication
hypertension
Journal
Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524
Informations de publication
Date de publication:
21 02 2023
21 02 2023
Historique:
pubmed:
9
2
2023
medline:
25
2
2023
entrez:
8
2
2023
Statut:
ppublish
Résumé
Background Hypertension is associated with gut dysbiosis, altered intestinal immunity, and gut pathology in animal models and humans. Although these findings have implicated impaired interactions between gut and gut microbiota in hypertension, little is known about the specific functional gut microbes that interact with intestinal mucosa. Methods and Results To identify these microbes, we sorted Immunoglobin A (IgA)-coated (IgA
Identifiants
pubmed: 36752270
doi: 10.1161/JAHA.122.027918
pmc: PMC10111478
doi:
Substances chimiques
Immunoglobulin A
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e027918Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL033610
Pays : United States
Organisme : NHLBI NIH HHS
ID : R37 HL033610
Pays : United States
Références
Hypertension. 2015 Jun;65(6):1331-40
pubmed: 25870193
Nat Microbiol. 2020 Mar;5(3):511-524
pubmed: 31988379
Hypertension. 2019 Mar;73(3):561-570
pubmed: 30636551
Cells. 2021 Jun 17;10(6):
pubmed: 34204247
Hypertension. 2022 Aug;79(8):1591-1601
pubmed: 35538603
Circ Res. 2017 Jan 20;120(2):312-323
pubmed: 27799253
Am J Physiol Heart Circ Physiol. 2022 Mar 1;322(3):H474-H485
pubmed: 35148233
Hypertension. 2015 Nov;66(5):1023-33
pubmed: 26351030
Cell Host Microbe. 2021 Jan 13;29(1):83-93.e3
pubmed: 33385335
Physiol Genomics. 2020 Mar 1;52(3):121-132
pubmed: 31869283
Hypertension. 2022 Oct;79(10):2239-2249
pubmed: 35950503
Science. 2017 Oct 20;358(6361):
pubmed: 28971969
Nat Rev Immunol. 2019 Aug;19(8):517-532
pubmed: 30992524
Circ Res. 2022 Feb 4;130(3):401-417
pubmed: 35113664
Cell. 2014 Aug 28;158(5):1000-1010
pubmed: 25171403