Metabolic individuality: Limitations, challenges, and potential for clinical utility.
Journal
Cell metabolism
ISSN: 1932-7420
Titre abrégé: Cell Metab
Pays: United States
ID NLM: 101233170
Informations de publication
Date de publication:
07 02 2023
07 02 2023
Historique:
entrez:
8
2
2023
pubmed:
9
2
2023
medline:
11
2
2023
Statut:
ppublish
Résumé
In Nature Medicine, Surendran and colleagues recently reported the analysis of human plasma metabolomic data for 913 metabolites in ∼20,000 individuals, identifying 2,599 metabolite-genetic variant associations and >400 metabolite signatures comprised of jointly regulated metabolites. This extensive atlas of variant-metabolite relationships reveals novel genomic mechanisms driving metabolic phenotypes.
Identifiants
pubmed: 36754017
pii: S1550-4131(23)00007-4
doi: 10.1016/j.cmet.2023.01.007
pii:
doi:
Types de publication
Journal Article
Comment
Langues
eng
Sous-ensembles de citation
IM
Pagination
233-235Commentaires et corrections
Type : CommentOn
Informations de copyright
Copyright © 2023 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of interests S.H.E. and J.E.P. are employees of Baylor College of Medicine, which derives revenue from genetic and metabolomic testing.