Autism under the umbrella of ESSENCE.

attention-deficit/hyperactivity disorder autism spectrum disorder comorbidity early symptomatic syndromes eliciting neurodevelopmental clinical examinations (ESSENCE) etiology intellectual disability intervention

Journal

Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006

Informations de publication

Date de publication:
2023
Historique:
received: 24 07 2022
accepted: 09 01 2023
entrez: 9 2 2023
pubmed: 10 2 2023
medline: 10 2 2023
Statut: epublish

Résumé

This brief article gives a short overview of "comorbidity" in autism. The most common co-occurring disorders will be presented and discussed within the context of ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations), a concept that provides a holistic perspective for neurodevelopmental disorders. The ESSENCE concept also considers the heterogeneous and changing clinical panorama of developmental disorders over time, and also the multifactorial etiologies, including so called behavioral phenotype syndromes. Aspects on behavioral interventions in autism are presented-interventions that need to be adapted and take into account all non-autism associated ESSENCE, including intellectual disability and Attention-Deficit/Hyperactivity Disorder (ADHD). The article also focuses on current research on pharmacological intervention based on the hypothesis of imbalance in excitatory/inhibitory transmitter systems in autism and some other ESSENCE.

Identifiants

pubmed: 36756219
doi: 10.3389/fpsyt.2023.1002228
pmc: PMC9901504
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1002228

Informations de copyright

Copyright © 2023 Fernell and Gillberg.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Elisabeth Fernell (E)

Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

Christopher Gillberg (C)

Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

Classifications MeSH