Magnetic resonance imaging of human variegated squirrel bornavirus 1 (VSBV-1) encephalitis reveals diagnostic pattern indistinguishable from Borna disease virus 1 (BoDV-1) encephalitis but typical for bornaviruses.
BoDV-1
Borna disease virus 1
Bornavirus
VSBV-1
basal ganglia
encephalitis
limbic system
variegated squirrel bornavirus 1
Journal
Emerging microbes & infections
ISSN: 2222-1751
Titre abrégé: Emerg Microbes Infect
Pays: United States
ID NLM: 101594885
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
pubmed:
10
2
2023
medline:
3
3
2023
entrez:
9
2
2023
Statut:
ppublish
Résumé
Human bornavirus encephalitis is an emerging disease caused by the variegated squirrel bornavirus 1 (VSBV-1) and the Borna disease virus 1 (BoDV-1). While characteristic brain magnetic resonance imaging (MRI) changes have been described for BoDV-1 encephalitis, only scarce diagnostic data in VSBV-1 encephalitis exist. We systematically analysed brain MRI scans from all known VSBV-1 encephalitis patients. Initial and follow-up scans demonstrated characteristic T2 hyperintense lesions in the limbic system and the basal ganglia, followed by the brainstem. No involvement of the cerebellar cortex was seen. Deep white matter affection occurred in a later stage of the disease. Strict symmetry of pathologic changes was seen in 62%. T2 hyperintense areas were often associated with low T1 signal intensity and with mass effect. Sinusitis in three patients on the first MRI and an early involvement of the limbic system suggest an olfactory route of VSBV-1 entry. The viral spread could occur
Identifiants
pubmed: 36757188
doi: 10.1080/22221751.2023.2179348
pmc: PMC9980399
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2179348Références
Lancet Infect Dis. 2020 Apr;20(4):467-477
pubmed: 31924550
Emerg Microbes Infect. 2022 Dec;11(1):6-13
pubmed: 34783638
Mol Psychiatry. 2012 May;17(5):486-93
pubmed: 22290118
Clin Microbiol Rev. 2003 Jul;16(3):534-45
pubmed: 12857781
Arch Virol. 2017 Sep;162(9):2747-2754
pubmed: 28593419
N Engl J Med. 2015 Jul 9;373(2):154-62
pubmed: 26154788
Euro Surveill. 2019 Feb;24(8):
pubmed: 30808439
BMC Infect Dis. 2021 Aug 10;21(1):787
pubmed: 34376142
N Engl J Med. 2018 Oct 4;379(14):1377-1379
pubmed: 30281984
Nervenarzt. 2022 Aug;93(8):835-837
pubmed: 35024881
Sci Rep. 2019 Dec 27;9(1):20154
pubmed: 31882942
Ann Neurol. 2020 Oct;88(4):723-735
pubmed: 32794235
Med Mal Infect. 2017 May;47(3):195-205
pubmed: 28268128
Emerg Infect Dis. 2021 May;27(5):1371-1379
pubmed: 33900167
Acta Neuropathol. 2019 Jun;137(6):1017-1019
pubmed: 30953131
Emerg Microbes Infect. 2022 Dec;11(1):1335-1338
pubmed: 35437118
Acta Neuropathol. 2019 Oct;138(4):653-665
pubmed: 31346692
Emerg Infect Dis. 2017 Mar;23(3):477-481
pubmed: 28221112
Int J Mol Sci. 2019 Mar 15;20(6):
pubmed: 30875911
Anim Health Res Rev. 2016 Dec;17(2):92-109
pubmed: 27212192
Emerg Infect Dis. 2018 Jun;24(6):978-987
pubmed: 29774846
N Engl J Med. 2020 Jul 2;383(1):83-85
pubmed: 32609989
N Engl J Med. 2018 Oct 4;379(14):1375-1377
pubmed: 30281979
PLoS One. 2014 Apr 03;9(4):e93659
pubmed: 24699636
Rev Med Virol. 2007 May-Jun;17(3):181-203
pubmed: 17342788
Microorganisms. 2021 May 25;9(6):
pubmed: 34070673
Emerg Microbes Infect. 2021 Dec;10(1):602-611
pubmed: 33706665
Emerg Infect Dis. 2019 Jun;25(6):1058-1065
pubmed: 31107210