A novel Cu(II)-based DNA-intercalating agent: Structural and biological insights using biophysical and in silico techniques.

Humans Intercalating Agents / chemistry Molecular Docking Simulation Ligands Coordination Complexes / chemistry Copper / chemistry DNA / chemistry Antineoplastic Agents / pharmacology
Copper(II) complex Cytotoxicity DFT DNA binding profile Molecular docking simulations QM/MM

Journal

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
ISSN: 1873-3557
Titre abrégé: Spectrochim Acta A Mol Biomol Spectrosc
Pays: England
ID NLM: 9602533

Informations de publication

Date de publication:
15 May 2023
Historique:
received: 23 10 2022
revised: 14 01 2023
accepted: 01 02 2023
pubmed: 10 2 2023
medline: 15 3 2023
entrez: 9 2 2023
Statut: ppublish

Résumé

A new mixed-ligand Cu(II) complex formulated as [Cu(dipic)(amp)(H

Identifiants

DOI: 10.1016/j.saa.2023.122438 PMID: 36758364
pubmed: 36758364
pii: S1386-1425(23)00123-3
doi: 10.1016/j.saa.2023.122438
pii:
doi:

Substances chimiques

Intercalating Agents 0
Ligands 0
Coordination Complexes 0
Copper 789U1901C5
DNA 9007-49-2
Antineoplastic Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

122438

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Elaheh Movahedi (E)

Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran.

Hafez Razmazma (H)

Laboratory of Computational Quantum Chemistry and Drug Design, Department of Chemistry, University of Sistan and Baluchestan, Zahedan, Iran.

Alireza Rezvani (A)

Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran. Electronic address: Ali@hamoon.usb.ac.ir.

Alireza Nowroozi (A)

Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran. Electronic address: Anowroozi@chem.usb.ac.ir.

Ali Ebrahimi (A)

Laboratory of Computational Quantum Chemistry and Drug Design, Department of Chemistry, University of Sistan and Baluchestan, Zahedan, Iran.

Vaclav Eigner (V)

Institute of Physics of the Czech Academy of Sciences, Na Slovance 2, 18221, Prague 8, Czech Republic.

Michal Dusek (M)

Institute of Physics of the Czech Academy of Sciences, Na Slovance 2, 18221, Prague 8, Czech Republic.

Farukh Arjmand (F)

Department of Chemistry, Aligarh Muslim University, Aligarh, UP 202002, India.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A novel Cu(II)-based DNA-intercalating agent:...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Intercalants › A novel Cu(II)-based DNA-intercalating agent:...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › A novel Cu(II)-based DNA-intercalating agent:...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › A novel Cu(II)-based DNA-intercalating agent:...
questionsmedicales.fr › Composés chimiques organiques › Complexes de coordination › A novel Cu(II)-based DNA-intercalating agent:...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Cuivre › A novel Cu(II)-based DNA-intercalating agent:...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › A novel Cu(II)-based DNA-intercalating agent:...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › A novel Cu(II)-based DNA-intercalating agent:...