Fertility Desire and Associations with Condomless Sex, Antiretroviral Adherence, and Transmission Potential in a Cohort of Kenyan Women Living with HIV in Sero-discordant Relationships: A Mixed Methods Study.
Fertility desire
Fertility intent
Sero-discordant partnerships
Women living with HIV
Journal
AIDS and behavior
ISSN: 1573-3254
Titre abrégé: AIDS Behav
Pays: United States
ID NLM: 9712133
Informations de publication
Date de publication:
Aug 2023
Aug 2023
Historique:
accepted:
23
01
2023
medline:
14
7
2023
pubmed:
10
2
2023
entrez:
9
2
2023
Statut:
ppublish
Résumé
For women living with HIV (WLH) in serodiscordant partnerships, decisions about childbearing can challenge condom use and antiretroviral adherence. In a prospective cohort of 148 WLH in serodiscordant partnerships, 58 (39%) wanted more children in the future but were not currently trying to conceive (fertility desire), and 32 (22%) were currently trying to become pregnant (fertility intent). Detection of prostate specific antigen (PSA) in vaginal secretions, a marker for recent condomless sex, was lowest in women with fertility desire and highest in women with fertility intent. Detectable viral load followed a similar pattern. Risk of HIV transmission, when condomless sex and PSA detection occurred concurrently, was three to fourfold higher at visits with fertility intent compared to visits with fertility desire. Qualitative interviews underscored the importance women place on childbearing and suggested that they had limited information about the role of antiretroviral therapy in reducing sexual HIV transmission.
Identifiants
pubmed: 36759394
doi: 10.1007/s10461-023-04004-4
pii: 10.1007/s10461-023-04004-4
pmc: PMC10338402
doi:
Substances chimiques
Prostate-Specific Antigen
EC 3.4.21.77
Anti-Retroviral Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2803-2814Subventions
Organisme : NICHD NIH HHS
ID : R01 HD072617
Pays : United States
Organisme : NICHD NIH HHS
ID : K24 HD088229
Pays : United States
Organisme : NIAID NIH HHS
ID : P30 AI027757
Pays : United States
Organisme : NCI NIH HHS
ID : K08 CA228761
Pays : United States
Organisme : NIMH NIH HHS
ID : MH123248
Pays : United States
Organisme : NIMH NIH HHS
ID : P30 MH123248
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI007140
Pays : United States
Informations de copyright
© 2023. The Author(s).
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