Prevalence and trends of perioperative major adverse cardiovascular and cerebrovascular events during cancer surgeries.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
10 02 2023
10 02 2023
Historique:
received:
30
05
2022
accepted:
08
02
2023
entrez:
10
2
2023
pubmed:
11
2
2023
medline:
15
2
2023
Statut:
epublish
Résumé
Major adverse cardiovascular and cerebrovascular events (MACCE) is an important cause of morbidity and mortality during perioperative period. In this study, we looked for national trends in perioperative MACCE and its components as well as cancer types associated with high rates of perioperative MACCE during major cancer surgeries. This study was a retrospective analysis of the National Inpatient Sample, 2005-2014. Hospitalizations for surgeries of prostate, bladder, esophagus, pancreas, lung, liver, colorectal, and breast among patients 40 years and greater were included in the analysis. MACCE was defined as a composite measure that included in-hospital all-cause mortality, acute myocardial infarction (AMI), and ischemic stroke. A total of 2,854,810 hospitalizations for major surgeries were included in this study. Of these, 67,316 (2.4%) had perioperative MACCE. Trends of perioperative MACCE showed that it decreased significantly for AMI, death and any MACCE, while stroke did not significantly change during the study period. Logistic regression analysis for perioperative MACCE by cancer types showed that surgeries for esophagus, pancreas, lung, liver, and colorectal cancers had significantly greater odds for perioperative MACCE. The surgeries identified to have greater risks for MACCE in this study could be risk stratified for better informed decision-making and management.
Identifiants
pubmed: 36765154
doi: 10.1038/s41598-023-29632-7
pii: 10.1038/s41598-023-29632-7
pmc: PMC9918731
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2410Informations de copyright
© 2023. The Author(s).
Références
Ann Oncol. 2006 Feb;17(2):297-303
pubmed: 16282243
J Atheroscler Thromb. 2018 Oct 1;25(10):994-1002
pubmed: 30224607
N Engl J Med. 2007 Feb 15;356(7):706-13
pubmed: 17301301
JAMA. 2014 Jul 16;312(3):259-68
pubmed: 25027141
Circulation. 1999 Sep 7;100(10):1043-9
pubmed: 10477528
Circulation. 2012 Jun 12;125(23):2873-91
pubmed: 22586281
Br J Anaesth. 2014 Oct;113(4):644-51
pubmed: 24928634
Surgery. 2012 Feb;151(2):171-82
pubmed: 21975292
CMAJ. 2012 Aug 7;184(11):1237-45
pubmed: 22733671
Circulation. 2011 Jul 26;124(4):381-7
pubmed: 21730309
N Engl J Med. 1977 Oct 20;297(16):845-50
pubmed: 904659
JAMA Cardiol. 2017 Feb 1;2(2):181-187
pubmed: 28030663
Am J Med. 2014 Jul;127(7):608-15
pubmed: 24680794
Eur Heart J. 2016 Jan 7;37(2):177-85
pubmed: 26330424
JAMA. 2013 Oct 9;310(14):1462-72
pubmed: 24101118
JAMA. 2017 Apr 25;317(16):1642-1651
pubmed: 28444280
Eur J Heart Fail. 2019 Dec;21(12):1515-1525
pubmed: 31321851
Lancet. 2008 May 31;371(9627):1839-47
pubmed: 18479744
J Am Coll Cardiol. 2012 Oct 16;60(16):1581-98
pubmed: 22958960