Any Role for Microbiota in Cholangiocarcinoma? A Comprehensive Review.
biliary tract cancer
cholangiocarcinoma
gut-liver axis
microbiota
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
19 01 2023
19 01 2023
Historique:
received:
05
12
2022
revised:
09
01
2023
accepted:
10
01
2023
entrez:
11
2
2023
pubmed:
12
2
2023
medline:
15
2
2023
Statut:
epublish
Résumé
Alterations in the human microbiota have been linked to carcinogenesis in several cancers. To date, few studies have addressed the role of the microbiota in cholangiocarcinoma (CCA). Our work aims to update the knowledge about the role of the microbiota in the CCA microenvironment, and to highlight possible novel insights for the development of new diagnostic, prognostic, or even therapeutic strategies. We thus conducted a review of the literature. In recent years, great progress has been made in understanding the pathogenesis, the clinical and histological behavior, and the molecular profile of CCA. Much evidence suggests that the bile microbiota plays an essential role in biliary diseases, including CCA. Some studies have demonstrated that alterations in the qualitative and quantitative composition of the intestinal commensal bacteria lead to overall cancer susceptibility through various pathways. Other studies suggest that the gut microbiota plays a role in the pathogenesis and/or progression of CCA. The clinical implications are far-reaching, and the role of the microbiota in the CCA microenvironment may lead to considering the exciting implications of implementing therapeutic strategies that target the microbiota-immune system axis.
Identifiants
pubmed: 36766711
pii: cells12030370
doi: 10.3390/cells12030370
pmc: PMC9913249
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Hepatol Res. 2011 Aug;41(8):746-53
pubmed: 21794037
Digestion. 2020;101 Suppl 1:136-145
pubmed: 32799195
World J Gastroenterol. 2015 Dec 28;21(48):13418-31
pubmed: 26730152
Nat Genet. 2015 Sep;47(9):1003-10
pubmed: 26258846
Nat Genet. 2013 Dec;45(12):1474-8
pubmed: 24185513
Intern Med. 2014;53(7):651-4
pubmed: 24694471
Lancet. 2014 Jun 21;383(9935):2168-79
pubmed: 24581682
J Hepatol. 2017 Dec;67(6):1298-1323
pubmed: 28802875
Aliment Pharmacol Ther. 2013 Mar;37(6):604-12
pubmed: 23384404
J Clin Transl Hepatol. 2023 Feb 28;11(1):174-187
pubmed: 36406312
Liver Int. 2019 May;39 Suppl 1:32-42
pubmed: 30829432
Clin Transl Gastroenterol. 2020 Dec 22;12(1):e00292
pubmed: 33464733
Cancers (Basel). 2022 Apr 24;14(9):
pubmed: 35565248
Clin Cancer Res. 2018 Mar 15;24(6):1277-1286
pubmed: 29138340
Hepatology. 2013 Feb;57(2):648-55
pubmed: 23055147
J Clin Invest. 2020 Oct 1;130(10):5380-5396
pubmed: 32663198
Nat Rev Immunol. 2016 May 27;16(6):341-52
pubmed: 27231050
Am J Pathol. 2006 Sep;169(3):877-88
pubmed: 16936263
Occup Environ Med. 2018 Mar;75(3):191-198
pubmed: 29133597
Immunology. 2016 Jan;147(1):1-10
pubmed: 26439191
J Clin Oncol. 2018 Jan 20;36(3):276-282
pubmed: 29182496
Cancer Causes Control. 2013 May;24(5):911-8
pubmed: 23408245
Nat Rev Gastroenterol Hepatol. 2020 Sep;17(9):557-588
pubmed: 32606456
Eur J Cancer Prev. 2012 Jan;21(1):24-31
pubmed: 21857525
BMC Cancer. 2019 Feb 28;19(1):185
pubmed: 30819129
J Hepatol. 2012 Jul;57(1):69-76
pubmed: 22420979
Jpn J Cancer Res. 1987 Nov;78(11):1187-92
pubmed: 2826375
Cureus. 2019 Jan 25;11(1):e3962
pubmed: 30956914
Cancer Discov. 2021 May;11(5):1248-1267
pubmed: 33323397
Int J Cancer. 2007 Feb 1;120(3):638-41
pubmed: 17109384
J Viral Hepat. 2013 May;20(5):297-305
pubmed: 23565610
PLoS One. 2021 Mar 9;16(3):e0247798
pubmed: 33690612
Gut. 2019 Aug;68(8):1356-1378
pubmed: 31154395
Hepatology. 2016 Sep;64(3):785-96
pubmed: 26940227
Ann Oncol. 2016 Sep;27(suppl 5):v28-v37
pubmed: 27664259
Indian J Gastroenterol. 2019 Feb;38(1):61-68
pubmed: 30628006
Cancer Res. 2016 Mar 15;76(6):1578-90
pubmed: 26979791
Trop Geogr Med. 1980 Jun;32(2):95-100
pubmed: 6252671
Liver Int. 2019 May;39 Suppl 1:19-31
pubmed: 30851228
United European Gastroenterol J. 2021 Dec;9(10):1128-1135
pubmed: 34533900
Hepatol Int. 2022 Feb;16(1):99-111
pubmed: 35064546
Br J Surg. 2004 Dec;91(12):1538-48
pubmed: 15549778
J Hematol Oncol. 2017 Jan 5;10(1):4
pubmed: 28057014
Horm Cancer. 2010 Jun;1(3):136-45
pubmed: 21761356
Cancer Cell. 2017 Jul 10;32(1):57-70.e3
pubmed: 28648284
Cancer Sci. 2010 Mar;101(3):579-85
pubmed: 20085587
Cell Rep. 2016 Feb 2;14(4):907-919
pubmed: 26804919
Nat Commun. 2015 Jan 22;6:6087
pubmed: 25608663
J Hepatobiliary Pancreat Sci. 2021 Dec;28(12):1047-1059
pubmed: 34053180
Hepatology. 2010 Jul;52(1):155-63
pubmed: 20578004
Cancer Discov. 2021 May;11(5):1014-1015
pubmed: 33947718
Hepatology. 2011 Aug;54(2):463-71
pubmed: 21538440
Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1423-1434
pubmed: 28645654
Cancer Discov. 2017 Oct;7(10):1116-1135
pubmed: 28667006
Cancer Control. 2017 Jul-Sep;24(3):1073274817729245
pubmed: 28975830
Eur J Gastroenterol Hepatol. 2022 Mar 1;34(3):338-344
pubmed: 34775457
Int J Mol Sci. 2021 Aug 18;22(16):
pubmed: 34445610
Ann Hepatol. 2022 Sep-Oct;27(5):100737
pubmed: 35809836
Hepatology. 2020 Mar;71(3):893-906
pubmed: 31298745
Environ Health. 2019 Aug 7;18(1):71
pubmed: 31391078
PLoS One. 2017 Oct 19;12(10):e0186643
pubmed: 29049401
Scand J Gastroenterol. 1995 Apr;30(4):372-6
pubmed: 7610355
Hepatology. 2013 Dec;58(6):2045-55
pubmed: 23775876
Am J Physiol Gastrointest Liver Physiol. 2012 Nov 15;303(10):G1077-86
pubmed: 22961800
World J Hepatol. 2021 Dec 27;13(12):2113-2127
pubmed: 35070012
Br J Cancer. 2019 Jan;120(2):165-171
pubmed: 30420614
Hepatology. 2018 Sep;68(3):949-963
pubmed: 29278425
N Engl J Med. 2012 Feb 9;366(6):539-51
pubmed: 22316447
Eur J Gastroenterol Hepatol. 2023 Mar 1;35(3):241-247
pubmed: 36708293
Inflamm Allergy Drug Targets. 2012 Dec;11(6):478-83
pubmed: 22920631
Nat Immunol. 2018 Feb;19(2):108-119
pubmed: 29348500
J Am Coll Surg. 2013 Oct;217(4):736-750.e4
pubmed: 23890842
J Hepatol. 2020 Jan;72(1):95-103
pubmed: 31536748
World J Gastroenterol. 2013 Dec 14;19(46):8780-8
pubmed: 24379600
Br J Cancer. 2022 Mar;126(5):693-705
pubmed: 34663949
Cancers (Basel). 2022 Mar 11;14(6):
pubmed: 35326593
Dig Dis Sci. 2011 Jun;56(6):1682-92
pubmed: 21181444
Immunity. 2014 Jul 17;41(1):49-61
pubmed: 25035953
Semin Liver Dis. 2004 May;24(2):115-25
pubmed: 15192785
Trends Cancer. 2019 Jun;5(6):335-350
pubmed: 31208696
Cancer Sci. 2004 Jul;95(7):592-5
pubmed: 15245596
Gut. 2001 Jun;48(6):816-20
pubmed: 11358902
J Hepatol. 2019 Jul;71(1):104-114
pubmed: 30910538
Oncologist. 2016 May;21(5):594-9
pubmed: 27000463
Front Cell Infect Microbiol. 2021 Nov 23;11:751795
pubmed: 34888258
IARC Monogr Eval Carcinog Risks Hum. 2012;100(Pt B):1-441
pubmed: 23189750
J Natl Cancer Inst. 2019 Dec 1;111(12):1263-1278
pubmed: 31127946
Sci Rep. 2017 Feb 15;7:42744
pubmed: 28198451
Hepatology. 2011 Jul;54(1):173-84
pubmed: 21488076
Aliment Pharmacol Ther. 2018 Apr;47(7):886-895
pubmed: 29411404