Discrimination between Complete versus Non-Complete Pathologic Response to Neoadjuvant Therapy Using Ultrasensitive Mutation Analysis: A Proof-of-Concept Study in
BRCA1 mutation
breast cancer
neoadjuvant chemotherapy
pathologic complete response
review
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
18 Jan 2023
18 Jan 2023
Historique:
received:
18
12
2022
revised:
06
01
2023
accepted:
13
01
2023
entrez:
11
2
2023
pubmed:
12
2
2023
medline:
15
2
2023
Statut:
epublish
Résumé
Neoadjuvant chemotherapy (NACT) for breast cancer (BC) often results in pathologic complete response (pCR), i.e., the complete elimination of visible cancer cells. It is unclear whether the use of ultrasensitive genetic methods may still detect residual BC cells in complete responders. Breast carcinomas arising in
Identifiants
pubmed: 36768191
pii: ijms24031870
doi: 10.3390/ijms24031870
pmc: PMC9914941
pii:
doi:
Substances chimiques
BRCA1 protein, human
0
BRCA1 Protein
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Russia Science Foundation
ID : 22-15-00266
Références
Breast J. 2018 May;24(3):269-277
pubmed: 28929593
Cancer Chemother Pharmacol. 2021 Sep;88(3):439-450
pubmed: 34080040
Breast Cancer Res Treat. 2018 Aug;171(1):85-94
pubmed: 29725888
Clin Cancer Res. 2013 Dec 1;19(23):6360-70
pubmed: 24298066
J Clin Oncol. 2018 Aug 1;36(22):2281-2287
pubmed: 29791287
Breast Cancer Res Treat. 2014 Dec;148(3):675-83
pubmed: 25414026
Cancer Discov. 2012 Jun;2(6):503-11
pubmed: 22628410
Cancer Lett. 2017 Jul 1;397:127-132
pubmed: 28377179
Cancer Genet. 2021 Aug;256-257:165-178
pubmed: 34186498
JAMA Oncol. 2020 May 1;6(5):744-748
pubmed: 32163106
Ann Oncol. 2014 Jun;25(6):1128-36
pubmed: 24618153
Breast. 2003 Oct;12(5):320-7
pubmed: 14659147
J Clin Oncol. 2010 Jan 20;28(3):375-9
pubmed: 20008645
Breast Cancer Res Treat. 2016 May;157(1):157-65
pubmed: 27113739
Hered Cancer Clin Pract. 2021 Aug 28;19(1):36
pubmed: 34454564
J Clin Oncol. 2020 May 10;38(14):1539-1548
pubmed: 32097092
Cancer Lett. 2022 Feb 1;526:41-52
pubmed: 34808283
Breast Cancer (Auckl). 2020 Dec 16;14:1178223420980377
pubmed: 33402827
Nat Med. 2018 May;24(5):628-637
pubmed: 29713086
Clin Cancer Res. 2020 Jun 15;26(12):2838-2848
pubmed: 32046998
Lancet. 2014 Jul 12;384(9938):164-72
pubmed: 24529560
Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):134-47
pubmed: 22144499
J Clin Oncol. 2011 Oct 1;29(28):3739-46
pubmed: 21900106
JAMA Oncol. 2017 Oct 01;3(10):1378-1385
pubmed: 28715532