Molecular Mechanisms of Carcinogenesis in Pediatric Airways Tumors.
children
molecular mechanisms
mucoepidermoid carcinoma
pediatric airways tumors
pediatric laryngeal tumors
recurrent respiratory papillomatosis
rhabdomyosarcoma
subglottic hemangioma
tumor biology
tumorigenesis
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
22 Jan 2023
22 Jan 2023
Historique:
received:
18
12
2022
revised:
15
01
2023
accepted:
18
01
2023
entrez:
11
2
2023
pubmed:
12
2
2023
medline:
15
2
2023
Statut:
epublish
Résumé
Primary tumors of the airways in the pediatric population are very rare entities. For this reason, little is known about the pathogenesis of these neoplasms. Understanding the biology has different practical implications: for example, it could help in the differential diagnosis, have a prognostic significance, or may lead to the development of a targeted therapy. The aim of this article is to present the current knowledge about pediatric airways tumors, focusing on the molecular mechanisms that cause the onset and progression of these neoplasms. After a brief introduction of epidemiology and clinical presentation, the tumorigenesis of the most frequent pediatric airways tumors will be described: Juvenile-onset recurrent respiratory papillomatosis (JORRP), Subglottic Hemangiona (SH), Rhabdomyosarcoma (RMS), and Mucoepidermoid carcinoma (MEC).
Identifiants
pubmed: 36768522
pii: ijms24032195
doi: 10.3390/ijms24032195
pmc: PMC9916405
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Cancer Genet Cytogenet. 2007 Apr 1;174(1):68-73
pubmed: 17350470
Diagnostics (Basel). 2020 Feb 20;10(2):
pubmed: 32093404
J Pediatr Surg. 1993 Sep;28(9):1133-6
pubmed: 8308677
Immunol Lett. 2017 Nov;191:31-34
pubmed: 28860041
Front Surg. 2014 Sep 25;1:38
pubmed: 25593962
Int J Pediatr Otorhinolaryngol. 2018 Oct;113:34-37
pubmed: 30174006
Pediatr Surg Int. 2016 Apr;32(4):417-24
pubmed: 26790674
Pediatr Ann. 2012 Aug;41(8):1-6
pubmed: 22881413
Laryngoscope. 1994 May;104(5 Pt 1):523-7
pubmed: 8189980
Front Oncol. 2019 Aug 02;9:682
pubmed: 31428574
BMC Cancer. 2015 Oct 26;15:803
pubmed: 26503699
Int J Pediatr Otorhinolaryngol. 2016 Nov;90:175-180
pubmed: 27729127
Microvasc Res. 1998 Jan;55(1):29-42
pubmed: 9473407
Arch Dis Child. 1997 May;76(5):458-9
pubmed: 9196368
J Thorac Dis. 2010 Mar;2(1):48-51
pubmed: 22263017
Growth Horm IGF Res. 2017 Apr;33:17-22
pubmed: 28129571
J Pediatr Surg. 2007 Jul;42(7):E23-9
pubmed: 17618868
J Infect Dis. 2013 Feb 15;207(4):583-7
pubmed: 23204170
J Med Chem. 2007 Aug 23;50(17):3984-4002
pubmed: 17665889
Pediatr Clin North Am. 1996 Dec;43(6):1385-401
pubmed: 8973518
JCI Insight. 2021 Apr 8;6(7):
pubmed: 33830080
Int J Pediatr Otorhinolaryngol. 2020 Jan;128:109697
pubmed: 31698245
J Clin Pathol. 2001 Mar;54(3):249-52
pubmed: 11253142
J Biol Chem. 2000 May 5;275(18):13802-11
pubmed: 10788502
Clin Diagn Lab Immunol. 2004 May;11(3):538-47
pubmed: 15138179
Curr Opin Otolaryngol Head Neck Surg. 2004 Dec;12(6):509-12
pubmed: 15548909
Int J Cancer. 2006 Jan 1;118(1):209-14
pubmed: 16003751
PLoS One. 2014 Jun 11;9(6):e99114
pubmed: 24918765
J Clin Pathol. 2011 Oct;64(10):870-4
pubmed: 21947300
Pediatr Dermatol. 2007 Jul-Aug;24(4):353-5
pubmed: 17845154
Mod Pathol. 2000 Aug;13(8):914-8
pubmed: 10955460
Mol Med. 2008 Sep-Oct;14(9-10):608-17
pubmed: 18607510
J Surg Res. 2009 Oct;156(2):224-30
pubmed: 19631347
JAMA Otolaryngol Head Neck Surg. 2017 Jun 1;143(6):614-622
pubmed: 28334393
J Dtsch Dermatol Ges. 2017 Dec;15(12):1185-1190
pubmed: 29193649
Front Immunol. 2022 Mar 08;13:849493
pubmed: 35350785
Otolaryngol Clin North Am. 2012 Jun;45(3):671-94, viii-ix
pubmed: 22588043
Springerplus. 2013 Apr 10;2(1):153
pubmed: 23641321
Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2664-70
pubmed: 17872454
Skelet Muscle. 2012 Dec 03;2(1):25
pubmed: 23206814
Radiat Oncol J. 2022 Sep;40(3):208-212
pubmed: 36200310
Ann Otol Rhinol Laryngol. 2011 Oct;120(10):627-34
pubmed: 22097147
Genes Chromosomes Cancer. 2010 Jan;49(1):59-69
pubmed: 19827123
Br J Cancer. 2015 Jan 20;112(2):227-31
pubmed: 25211658
World J Pediatr. 2022 Feb;18(2):75-82
pubmed: 35072893
APMIS. 2010 Jun;118(6-7):422-49
pubmed: 20553526
Med Hypotheses. 2008;70(4):815-8
pubmed: 17888584
N Engl J Med. 2008 Jun 12;358(24):2649-51
pubmed: 18550886
Case Rep Oncol. 2011 Mar 23;4(1):162-71
pubmed: 21526134
PLoS One. 2019 Jun 13;14(6):e0216697
pubmed: 31194767
Pediatr Res. 2019 Aug;86(2):202-207
pubmed: 31091531
Cell Rep. 2021 Feb 23;34(8):108768
pubmed: 33626346
Nat Rev Cancer. 2007 Mar;7(3):169-81
pubmed: 17318210
Pediatr Dev Pathol. 2001 Jan-Feb;4(1):68-72
pubmed: 11200493
Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1445-50
pubmed: 19164581
Arch Pathol Lab Med. 2008 Jul;132(7):1079-103
pubmed: 18605764
Clin Cancer Res. 2012 Apr 1;18(7):1925-35
pubmed: 22322668
Virology. 2013 Oct;445(1-2):169-74
pubmed: 23800545
Angiogenesis. 2009;12(2):197-207
pubmed: 19430954
Clin Respir J. 2017 May;11(3):346-351
pubmed: 26148572
JAMA Otolaryngol Head Neck Surg. 2015 Jan;141(1):78-83
pubmed: 25393901
Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10616-21
pubmed: 23754386
Lung Cancer. 2009 Jan;63(1):159-60
pubmed: 18992960
Clin Diagn Lab Immunol. 1994 May;1(3):357-60
pubmed: 7496977
Curr Opin Pediatr. 2014 Feb;26(1):50-6
pubmed: 24326270
Br J Dermatol. 2010 Aug;163(2):269-74
pubmed: 20456345
Carcinogenesis. 2003 Feb;24(2):159-69
pubmed: 12584163
Acta Otorhinolaryngol Ital. 2014 Dec;34(6):375-81
pubmed: 25762828
J Plast Reconstr Aesthet Surg. 2011 Jun;64(6):759-65
pubmed: 20870476
Otolaryngol Clin North Am. 2008 Oct;41(5):903-11, viii-ix
pubmed: 18775341
Cancers (Basel). 2020 Oct 01;12(10):
pubmed: 33019611
Laryngoscope. 2002 Nov;112(11):1926-9
pubmed: 12439156
Ear Nose Throat J. 2022 Nov;101(9):584-586
pubmed: 33236919
Case Rep Oncol Med. 2013;2013:625243
pubmed: 24303221
Respir Med. 2017 May;126:116-121
pubmed: 28427542
Am J Surg Pathol. 2010 Aug;34(8):1106-21
pubmed: 20588178
Lung Cancer. 2008 Jul;61(1):30-4
pubmed: 18192072
Oncogene. 2014 Dec 11;33(50):5697-705
pubmed: 24292683
J Huazhong Univ Sci Technolog Med Sci. 2009 Oct;29(5):614-9
pubmed: 19821096
Clin Immunol. 2001 Oct;101(1):94-9
pubmed: 11580231
J Indian Assoc Pediatr Surg. 2020 Mar-Apr;25(2):96-102
pubmed: 32139988
Int J Pediatr Otorhinolaryngol. 1999 Jun 15;49(1):1-14
pubmed: 10428400
Hum Immunol. 2004 Aug;65(8):773-82
pubmed: 15336778
Arch Pathol Lab Med. 2002 Oct;126(10):1184-8
pubmed: 12296755
Int J Pediatr Otorhinolaryngol. 2021 Jan;140:110507
pubmed: 33279850
Clin Exp Immunol. 2020 Feb;199(2):131-142
pubmed: 31628850
Int J Pediatr Otorhinolaryngol. 1998 Oct 15;45(3):265-73
pubmed: 9865445
J Oral Pathol Med. 2020 May;49(5):386-394
pubmed: 31661572
Obstet Gynecol. 2003 Apr;101(4):645-52
pubmed: 12681865
J Laryngol Otol. 1994 Mar;108(3):226-9
pubmed: 8169504
Life (Basel). 2021 Nov 22;11(11):
pubmed: 34833157
Nat Genet. 2003 Feb;33(2):208-13
pubmed: 12539049
APMIS. 2010 Jun;118(6-7):450-4
pubmed: 20553527
Int J Clin Exp Pathol. 2013 Dec 15;7(1):48-55
pubmed: 24427325
Arch Otolaryngol Head Neck Surg. 1999 Jul;125(7):743-8
pubmed: 10406310