Evaluation of Children with Malignancies for Blood and Marrow Transplantation: A Report from the ASTCT Committee on Practice Guidelines.

Pediatric hematopoietic cell transplantation Pediatric malignancy Pretransplantation evaluation Transplantation candidate

Journal

Transplantation and cellular therapy
ISSN: 2666-6367
Titre abrégé: Transplant Cell Ther
Pays: United States
ID NLM: 101774629

Informations de publication

Date de publication:
05 2023
Historique:
received: 03 02 2023
accepted: 03 02 2023
medline: 1 5 2023
pubmed: 13 2 2023
entrez: 12 2 2023
Statut: ppublish

Résumé

Evaluation of a candidate for hematopoietic cell transplantation (HCT) is a complex process with substantial intercenter variability. Although literature providing guidance for evaluating the eligibility of adults is well established, similar guidance for children is lacking. To address gaps between adult recommendations and the specific needs of children, we convened a panel of pediatric HCT experts from a wide geographic range of American Society of Transplantation and Cellular Therapy (ASTCT) member institutions to offer recommendations for pediatric-focused pre-HCT evaluation. In this report from the ASTCT Committee on Practice Guidelines, we present a practical framework for evaluating children with malignancies who are candidates for HCT. We also highlight key differences from adults and emphasize areas of unmet need that require additional research to delineate best practices.

Identifiants

pubmed: 36775202
pii: S2666-6367(23)01070-9
doi: 10.1016/j.jtct.2023.02.003
pii:
doi:

Types de publication

Practice Guideline Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

293-301

Informations de copyright

Copyright © 2023 The American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc. All rights reserved.

Auteurs

Ellen Fraint (E)

Division of Pediatric Hematology, Oncology, and Cellular Therapy, Children's Hospital at Montefiore, Bronx, New York. Electronic address: ellen.fraint@einsteinmed.edu.

Hisham Abdel-Azim (H)

Loma Linda University School of Medicine, Cancer Center, Children's Hospital and Medical Center, Loma Linda, California.

Neel S Bhatt (NS)

Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.

Larisa Broglie (L)

Medical College of Wisconsin, Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood and Marrow Transplantation, Milwaukee, Wisconsin.

Asma Chattha (A)

Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota.

Mira Kohorst (M)

Department of Pediatric and Adolescent Medicine, Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, Minnesota.

Yiouli P Ktena (YP)

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.

Michelle A Lee (MA)

Division of Pediatric Hematology, Oncology, and Cellular Therapy, Children's Hospital at Montefiore, Bronx, New York.

Susie Long (S)

University of Minnesota Masonic Children's Hospital, MHealth Fairview Acute Care Pharmacy Services, Minneapolis, Minnesota.

Muna Qayed (M)

Aflac Cancer and Blood Disorders Center, Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia.

Akshay Sharma (A)

Department of Bone Marrow Transplantation and Cellular Therapy, St Jude Children's Research Hospital, Memphis, Tennessee.

Heather Stefanski (H)

National Marrow Donor Program, Minneapolis, Minnesota.

Anant Vatsayan (A)

Children's National Medical Center, Washington, District of Columbia.

Lisa Wray (L)

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Mehdi Hamadani (M)

BMT & Cellular Therapy Program, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.

Paul A Carpenter (PA)

Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.

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Classifications MeSH