Regions of Highly Recurrent Electrogram Morphology With Low Cycle Length Reflect Substrate for Atrial Fibrillation.

AF, atrial fibrillation AI, anisotropy index CFAE, complex fractionated atrial electrogram CLR, cycle length of the most recurrent electrogram morphology DF, dominant frequency EGM, electrogram EMR, electrogram morphology recurrence FFT, fast Fourier transform FI, fractionation interval FIRM, focal impulse and rotor mapping LAA, left atrial appendage LAFW, left atrial free wall LAT, local activation time OI, organization index PLA, posterior left atrium PV, pulmonary vein RAA, right atrial appendage RAFW, right atrial free wall RAP, rapid atrial pacing Rec%, recurrence percentage ShEn, Shannon’s entropy arrhythmias atrial fibrillation fibrosis mapping

Journal

JACC. Basic to translational science
ISSN: 2452-302X
Titre abrégé: JACC Basic Transl Sci
Pays: United States
ID NLM: 101677259

Informations de publication

Date de publication:
Jan 2023
Historique:
received: 20 12 2021
revised: 20 07 2022
accepted: 20 07 2022
entrez: 13 2 2023
pubmed: 14 2 2023
medline: 14 2 2023
Statut: epublish

Résumé

Traditional anatomically guided ablation and attempts to perform electrogram-guided atrial fibrillation (AF) ablation (CFAE, DF, and FIRM) have not been shown to be sufficient treatment for persistent AF. Using biatrial high-density electrophysiologic mapping in a canine rapid atrial pacing model of AF, we systematically investigated the relationship of electrogram morphology recurrence (EMR) (Rec% and CL

Identifiants

pubmed: 36777167
doi: 10.1016/j.jacbts.2022.07.011
pii: S2452-302X(22)00324-2
pmc: PMC9911322
doi:

Types de publication

Journal Article

Langues

eng

Pagination

68-84

Informations de copyright

© 2022 Published by Elsevier on behalf of the American College of Cardiology Foundation.

Déclaration de conflit d'intérêts

Dr Arora is supported by National Institutes of Health grants R01 HL093490; R01 HL140061; an AHA Strategically Focused Research Networks AF Center grant; and by the NIH Center for Accelerated Innovations at Cleveland Clinic (NCAI-CC). Dr Arora has ownership interest in Rhythm Therapeutics. Dr Pfenniger is supported by grant KL2TR001424. All authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Références

Heart Rhythm. 2014 Nov;11(11):2027-34
pubmed: 25101485
Circ Res. 2018 Mar 2;122(5):752-773
pubmed: 29496798
N Engl J Med. 2015 May 7;372(19):1812-22
pubmed: 25946280
Circ Arrhythm Electrophysiol. 2011 Aug;4(4):470-7
pubmed: 21536597
Heart Rhythm. 2007 Mar;4(3 Suppl):S13-6
pubmed: 17336877
Int J Cardiol. 2015 Nov 15;199:407-14
pubmed: 26253050
J Cardiovasc Electrophysiol. 2015 Dec;26(12):1361-3
pubmed: 26359793
J Am Coll Cardiol. 2007 Mar 27;49(12):1340-8
pubmed: 17394967
Comput Biol Med. 2015 Oct 1;65:220-8
pubmed: 26255963
Europace. 2019 Oct 1;21(10):1484-1493
pubmed: 31280323
J Cardiovasc Electrophysiol. 2007 Jun;18(6):680-5
pubmed: 17472716
Circ Arrhythm Electrophysiol. 2012 Aug 1;5(4):650-8
pubmed: 22722660
Circulation. 1998 Sep 22;98(12):1236-48
pubmed: 9743516
Heart Rhythm. 2007 Sep;4(9):1225-34
pubmed: 17765627
Circulation. 1989 Jul;80(1):112-9
pubmed: 2736743
Circulation. 2002 May 21;105(20):2442-8
pubmed: 12021234
Heart Rhythm. 2009 Jan;6(1):33-40
pubmed: 19121797
Circulation. 1994 Apr;89(4):1665-80
pubmed: 8149534
Circulation. 2004 Jun 22;109(24):3007-13
pubmed: 15184286
Circ Arrhythm Electrophysiol. 2013 Feb;6(1):48-57
pubmed: 23264437
J Cardiovasc Electrophysiol. 2000 Aug;11(8):869-79
pubmed: 10969749
Circ Arrhythm Electrophysiol. 2012 Apr;5(2):361-70
pubmed: 22423141
Circulation. 1998 Oct 27;98(17):1790-5
pubmed: 9788835
J Am Coll Cardiol. 2011 Feb 15;57(7):831-8
pubmed: 21310320
Pacing Clin Electrophysiol. 2019 Dec;42(12):1503-1516
pubmed: 31609005
Circ Arrhythm Electrophysiol. 2012 Aug 1;5(4):640-9
pubmed: 22722658
Circ Res. 2014 Apr 25;114(9):1500-15
pubmed: 24763467
J Am Coll Cardiol. 2002 Nov 20;40(10):1831-40
pubmed: 12446068
Circ Arrhythm Electrophysiol. 2016 Nov;9(11):
pubmed: 27906655
Am J Physiol Heart Circ Physiol. 2008 Jan;294(1):H134-44
pubmed: 17982017
Pacing Clin Electrophysiol. 1978 Oct;1(4):426-38
pubmed: 95635
Heart Rhythm. 2013 Dec;10(12):1830-8
pubmed: 24016695
Heart Rhythm. 2015 Jul;12(7):1415-23
pubmed: 25771914
Cardiovasc Res. 2011 Mar 1;89(4):766-75
pubmed: 21097807
J Cardiovasc Electrophysiol. 2007 Jul;18(7):757-64
pubmed: 17578346
Comput Biol Med. 2013 Dec;43(12):2127-35
pubmed: 24290930
J Cardiovasc Electrophysiol. 2018 Apr;29(4):514-522
pubmed: 29369468
Heart Rhythm. 2016 Dec;13(12):2331-2332
pubmed: 27567938
Circ Res. 2007 Oct 12;101(8):743-5
pubmed: 17932329
Card Electrophysiol Clin. 2019 Dec;11(4):563-571
pubmed: 31706465
JCI Insight. 2019 Oct 17;4(20):
pubmed: 31503549
Circulation. 2001 May 29;103(21):2631-6
pubmed: 11382735
Pacing Clin Electrophysiol. 2011 Oct;34(10):1267-77
pubmed: 21651593
Circ Arrhythm Electrophysiol. 2011 Jun;4(3):388-96
pubmed: 21421805
Circulation. 1992 Aug;86(2):375-82
pubmed: 1638706
Physiol Rev. 2007 Apr;87(2):425-56
pubmed: 17429037
Physiol Rev. 2011 Jan;91(1):265-325
pubmed: 21248168
J Am Coll Cardiol. 2004 Jun 2;43(11):2044-53
pubmed: 15172410
JAMA. 2014 Feb 5;311(5):498-506
pubmed: 24496537
Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2911-23
pubmed: 16877548
Circulation. 1996 Feb 1;93(3):513-8
pubmed: 8565169
Ann Thorac Surg. 1996 Jan;61(1):104-11; discussion 111-2
pubmed: 8561533
J Cell Mol Med. 2020 Jul;24(14):7751-7766
pubmed: 32441464
Heart Rhythm. 2012 Sep;9(9):1436-9
pubmed: 22465458
Heart Rhythm. 2011 Sep;8(9):1357-63
pubmed: 21699826
Circ Res. 2014 Apr 25;114(9):1516-31
pubmed: 24763468
N Engl J Med. 1998 Sep 3;339(10):659-66
pubmed: 9725923
Circulation. 2005 Aug 9;112(6):789-97
pubmed: 16061740
Mod Concepts Cardiovasc Dis. 1962 Aug;31:739-44
pubmed: 14474971
J Am Heart Assoc. 2013 Mar 18;2(2):e004549
pubmed: 23537812
Circulation. 2020 Sep 29;142(13):1261-1278
pubmed: 32686471
Circulation. 2004 Jan 27;109(3):327-34
pubmed: 14707026
Circulation. 2003 Apr 8;107(13):1816-21
pubmed: 12665495
Circulation. 2000 Jan 18;101(2):194-9
pubmed: 10637208
J Thorac Cardiovasc Surg. 1991 Apr;101(4):569-83
pubmed: 2008095

Auteurs

Shin Yoo (S)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Markus Rottmann (M)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Jason Ng (J)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

David Johnson (D)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Bassel Shanab (B)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Anna Pfenniger (A)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Gail Elizabeth Geist (GE)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Suman Mandava (S)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Amy Burrell (A)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Wenwei Zhang (W)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

J Andrew Wasserstrom (JA)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Bradley P Knight (BP)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Rod Passman (R)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Jeffrey J Goldberger (JJ)

University of Miami Miller School of Medicine, Miami, Florida, USA.

Rishi Arora (R)

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Classifications MeSH