Identification of PCSK9-like human gene knockouts using metabolomics, proteomics, and whole-genome sequencing in a consanguineous population.
consanguineous population
drug target validation, drug target identification
human gene knockouts
metabolomics
proteomics
whole-genome sequencing
Journal
Cell genomics
ISSN: 2666-979X
Titre abrégé: Cell Genom
Pays: United States
ID NLM: 9918284260106676
Informations de publication
Date de publication:
11 Jan 2023
11 Jan 2023
Historique:
received:
10
02
2022
revised:
16
07
2022
accepted:
25
10
2022
entrez:
13
2
2023
pubmed:
14
2
2023
medline:
14
2
2023
Statut:
epublish
Résumé
Natural human knockouts of genes associated with desirable outcomes, such as
Identifiants
pubmed: 36777185
doi: 10.1016/j.xgen.2022.100218
pii: S2666-979X(22)00171-9
pmc: PMC9903797
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100218Informations de copyright
© 2022 The Author(s).
Déclaration de conflit d'intérêts
E.B.F. is an employee of Pfizer.
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