tRNA m

RNA methylation RNA structure SHAPE RNA structure probing SPOUT methyltransferase substrate recognition transfer RNA (tRNA)

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
19 Oct 2023
Historique:
pubmed: 14 2 2023
medline: 14 2 2023
entrez: 13 2 2023
Statut: epublish

Résumé

The methyltransferase Trm10 modifies a subset of tRNAs on the base N1 position of the 9th nucleotide in the tRNA core. Trm10 is conserved throughout Eukarya and Archaea, and mutations in the human gene (

Identifiants

pubmed: 36778341
doi: 10.1101/2023.02.01.526536
pmc: PMC9915607
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM130135
Pays : United States
Organisme : NIH HHS
ID : S10 OD023582
Pays : United States

Commentaires et corrections

Type : UpdateIn

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Auteurs

Sarah E Strassler (SE)

Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road NE, Atlanta GA, 30322, USA.
Graduate Program in Biochemistry, Cell and Developmental Biology, Graduate Division of Biological and Biomedical Sciences, Emory University.

Isobel E Bowles (IE)

Department of Chemistry and Biochemistry, Center for RNA Biology and Ohio State Biochemistry Program, 484 W. 12 Avenue, Columbus, OH, 43210, USA.
Ohio State Biochemistry Program, The Ohio State University, 484 W. 12 Avenue, Columbus, OH, 43210, USA.

Aiswarya Krishnamohan (A)

Department of Chemistry and Biochemistry, Center for RNA Biology and Ohio State Biochemistry Program, 484 W. 12 Avenue, Columbus, OH, 43210, USA.
Ohio State Biochemistry Program, The Ohio State University, 484 W. 12 Avenue, Columbus, OH, 43210, USA.

Hyejeong Kim (H)

Department of Chemistry and Biochemistry, Center for RNA Biology and Ohio State Biochemistry Program, 484 W. 12 Avenue, Columbus, OH, 43210, USA.

Catherine B Edgington (CB)

Department of Chemistry and Biochemistry, Center for RNA Biology and Ohio State Biochemistry Program, 484 W. 12 Avenue, Columbus, OH, 43210, USA.

Emily G Kuiper (EG)

Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road NE, Atlanta GA, 30322, USA.
Graduate Program in Biochemistry, Cell and Developmental Biology, Graduate Division of Biological and Biomedical Sciences, Emory University.

Clio J Hancock (CJ)

Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road NE, Atlanta GA, 30322, USA.

Lindsay R Comstock (LR)

Department of Chemistry, Wake Forest University, 1834 Wake Forest Road, Winston-Salem, NC 27106, USA.

Jane E Jackman (JE)

Department of Chemistry and Biochemistry, Center for RNA Biology and Ohio State Biochemistry Program, 484 W. 12 Avenue, Columbus, OH, 43210, USA.
Ohio State Biochemistry Program, The Ohio State University, 484 W. 12 Avenue, Columbus, OH, 43210, USA.

Graeme L Conn (GL)

Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road NE, Atlanta GA, 30322, USA.
Graduate Program in Biochemistry, Cell and Developmental Biology, Graduate Division of Biological and Biomedical Sciences, Emory University.

Classifications MeSH