Transmission mode and dispersal traits correlate with host specificity in mammalian gut microbes.
aerobe
anaerobe
generalist microbe
horizontal transmission
oxygen tolerance
phylosymbiosis
specialist microbe
spore
sporulation
vertical transmission
Journal
Molecular ecology
ISSN: 1365-294X
Titre abrégé: Mol Ecol
Pays: England
ID NLM: 9214478
Informations de publication
Date de publication:
14 Feb 2023
14 Feb 2023
Historique:
revised:
24
11
2022
received:
30
08
2022
accepted:
09
01
2023
pubmed:
15
2
2023
medline:
15
2
2023
entrez:
14
2
2023
Statut:
aheadofprint
Résumé
Different host species associate with distinct gut microbes in mammals, a pattern sometimes referred to as phylosymbiosis. However, the processes shaping this host specificity are not well understood. One model proposes that barriers to microbial transmission promote specificity by limiting microbial dispersal between hosts. This model predicts that specificity levels measured across microbes is correlated to transmission mode (vertical vs. horizontal) and individual dispersal traits. Here, we leverage two large publicly available gut microbiota data sets (1490 samples from 195 host species) to test this prediction. We found that host specificity varies widely across bacteria (i.e., there are generalist and specialist bacteria) and depends on transmission mode and dispersal ability. Horizontally-like transmitted bacteria equipped with traits that facilitate switches between host (e.g., tolerance to oxygen) were found to be less specific (more generalist) than microbes without those traits, for example, vertically-like inherited bacteria that are intolerant to oxygen. Altogether, our findings are compatible with a model in which limited microbial dispersal abilities foster host specificity.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Banting Postdoctoral fellowship (Canada)
Organisme : Swiss National Fondation (grant #20181001)
Organisme : Human Frontier Science Program
ID : RGY0078/2015
Informations de copyright
© 2023 The Authors. Molecular Ecology published by John Wiley & Sons Ltd.
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