Surface-Functionalized Metal-Organic Frameworks for Binding Coronavirus Proteins.

SARS-CoV-2 antiviral drugs metal−organic framework protein binding water adsorption

Journal

ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991

Informations de publication

Date de publication:
14 Feb 2023
Historique:
entrez: 14 2 2023
pubmed: 15 2 2023
medline: 15 2 2023
Statut: aheadofprint

Résumé

Since the outbreak of SARS-CoV-2, a multitude of strategies have been explored for the means of protection and shielding against virus particles: filtration equipment (PPE) has been widely used in daily life. In this work, we explore another approach in the form of deactivating coronavirus particles through selective binding onto the surface of metal-organic frameworks (MOFs) to further the fight against the transmission of respiratory viruses. MOFs are attractive materials in this regard, as their rich pore and surface chemistry can easily be modified on demand. The surfaces of three MOFs, UiO-66(Zr), UiO-66-NH

Identifiants

pubmed: 36786318
doi: 10.1021/acsami.2c21187
pmc: PMC9940617
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Aamod V Desai (AV)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Simon M Vornholt (SM)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Louise L Major (LL)

School of Biology, University of St Andrews, Biomedical Sciences Research Complex North Haugh, St Andrews KY16 9ST, U.K.

Romy Ettlinger (R)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Christian Jansen (C)

Institut für Anorganische Chemie und Strukturchemie, Heinrich-Heine-Universität Düsseldorf, 40204 Düsseldorf, Germany.

Daniel N Rainer (DN)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Richard de Rome (R)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Venus So (V)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Paul S Wheatley (PS)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Ailsa K Edward (AK)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Caroline G Elliott (CG)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Atin Pramanik (A)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Avishek Karmakar (A)

Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States of America.

A Robert Armstrong (AR)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Christoph Janiak (C)

Institut für Anorganische Chemie und Strukturchemie, Heinrich-Heine-Universität Düsseldorf, 40204 Düsseldorf, Germany.

Terry K Smith (TK)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.
School of Biology, University of St Andrews, Biomedical Sciences Research Complex North Haugh, St Andrews KY16 9ST, U.K.

Russell E Morris (RE)

EastChem School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, U.K.

Classifications MeSH